Genome Engineering and Synthetic Biology: Tools and Technologies

THIS CONFERENCE IS SOLD OUT
28-29 JANUARY 2016, GHENT, BELGIUM
Get the latest updates about the meeting by following #GESB16
Presenting the 2nd edition
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Genome Engineering and Synthetic Biology: Tools and Technologies
THIS CONFERENCE IS SOLD OUT

 

Genome Engineering and Synthetic Biology are revolutionizing Life Sciences. Driven by advances in the CRISPR-toolbox for rapid, cheap, multiplex modification of genomes and breakthroughs in DNA synthesis technologies, the pace of progress enabled by these tools in the last 2 years has been breathtaking.

The 1st Genome Engineering and Synthetic Biology: Tools and Technologies meeting (GESB) in September 2013 was a roaring success and we are pleased to announce the 2nd edition of GESB in January, 2016. The symposium will bring together some of the most highly regarded Academics and Companies in the world with novel technologies in several sessions, with topics focused on:

  • CRISPR and Synthetic Biology Tools
  • Gene and Genome assembly
  • CRISPR for re-engineering cellular systems
  • Future CRISPR applications
  • Expanding the Genetic Code

In addition to a great scientific and technology program, the conference will provide ample opportunities to network during the breaks, poster sessions, the conference dinner and our ‘Meet the Expert’ session!

‘Meet the Expert’ session with MIT Prof Christopher Voigt
We offer all junior researchers an opportunity to join speaker Christopher Voigt in a 'Meet the Expert' session during the conference. You will have the opportunity to ask any question/advise/feedback related to your research project/your research during an informal round table discussion. If you are interested in joining the session then send an e-mail to conferences@vib.be and let us know. Seating is very limited so make sure to reserve a spot soon!

Precision Genome Engineering Training Day on January 27, 2016 in Ghent, Belgium
The conference is preceded by a day of training, organized by Training at VIB, focused on precision genome engineering. The focus of this training is specifically on the practical use of the technology and on experiences gained applying genome engineering technologies in the lab. Registration and more info on the training day can be found on the training website.


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Top speakers: 

Martin Fussenegger

ETH Zurich, CH

Jin-Soo Kim

Seoul National University, KR

Emily LeProust

CEO, Twist Bioscience, US

Tom Henley

Associate Director of R&D, Horizon Discovery PLC, UK

Dan Voytas

CSO, Calyxt, US

Kevin Munnelly

CEO, Gen9, US

Christopher Voigt

MIT, Cambridge, US

Dan Gibson

J. Craig Venter Institute, US

Farren Isaacs

Yale University, USA

Randall Platt (Group of Feng Zhang)

Broad Institute of MIT and Harvard, US

Narendra Maheshri

Organism Engineer, Ginkgo Bioworks, US

Charles A. Gersbach

Duke University, US

Floyd Romesberg

The Scripps Research Institute, US

Bill Skarnes

Wellcome Trust Sanger Institute, UK

Mark Behlke

CSO, Integrated DNA Technologies, US

Jay Konieczka

COO, enEvolv, US

Riley Doyle

CEO and Technical Lead, Desktop Genetics, UK

Hanne Volpin

Danziger Innovations, IL

Caixia Gao

State Key Laboratory of Plant Cell and Chromosome Engineering, Beijing, CN

Court Turner

CEO, Synthorx, USA

Marvin Y. Ouyang

Vice President, Technologies, Cyagen Biosciences Inc.

Benjamin P. Kleinstiver

Harvard Medical School, US

Weizhi Ji

The Yunnan Key Laboratory of Primate Biomedical Research, CN

Lothar Steidler

Vice President, Intrexon Actobiotics NV, BE

Stefan Jakobs

Max Planck Institute for Biophysical Chemistry, DE

David Bikard

Head of the Synthetic Biology Group Institut Pasteur & the CSO of Eligo Biosciences, FR

Qingzhou Ji

Principal Scientist, MilliporeSigma, A business of Merck KGaA, Darmstadt, DE

Dietmar Schmucker

VIB Vesalius Research Center, KU Leuven
Download the program: 

Day 1 - 28 January 2016

Thursday, 28 January, 2016
08:45 - 09:15
Registration and Welcome coffee
Minneplein
09:15 - 12:45
Plenary Session: The Genome Engineering Revolution: CRISPR and SynBio
Van Rysselberghezaal

Chair: Jo Bury

09:15 - 09:20
Welcome
Jo Bury
Managing Director VIB, BE
Academic speaker
Watch the video of this talk
Jo Bury, General Director VIB, BE
09:20 - 09:55
Genome editing in human stem cells, animals, and plants
Jin-Soo Kim
Seoul National University, KR
Academic speaker
09:55 - 10:20
Engineering and Construction of Genes to Genomes
Kevin Munnelly
CEO, Gen9, US
Company speaker
10:20 - 10:25
Sponsor Talk: Genome engeneering by GeneArt
Axel Trefzer
Director research and development Synthetic Biology, ThermoFisher
Company speaker
10:25 - 10:30
Sponsors Talk: Eppendorf, your partner in genetic engineering
Daisy Dieltiens
Sales Specialist, Eppendorf, BE
Company speaker
10:30 - 10:35
Sponsor Talk: GenScript: Your Partner in Biomedical Research
Emma Zhang
Regional Sales Manager, GenScript, CN
Company speaker
10:35 - 11:10
Precision plant breeding using genome editing technologies
Caixia Gao
State Key Laboratory of Plant Cell and Chromosome Engineering, Beijing, CN
Academic speaker
11:10 - 11:30
Coffee Break
11:30 - 11:55
Rewriting DNA Synthesis
Emily LeProust
CEO, Twist Bioscience, US
Company speaker
Watch the video of this talk
Emily LeProust, CEO, Twist Bioscience, US
11:55 - 12:00
Sponsor Talk: Rapid and Low-cost Screening of Mutations Through Capillary Electrophoresis
Danilo Tait
European Director, Advanced Analytical Technologies, CH
Company speaker
12:00 - 12:05
Sponsor Talk: Genome Editing and Engineering Tools
Bert Depré
Account Manager Life Science Products, Bio-Connect, NL
Company speaker
12:05 - 12:10
Sponsor Talk: Publishing with eLife
Kora Korzec
Marketing Manager, eLife Sciences, UK
Company speaker
12:10 - 12:45
Prosthetic Gene Networks for Biomedical Applications
Martin Fussenegger
ETH Zurich, CH
Academic speaker
12:45 - 13:45
Lunch
Minneplein
13:45 - 16:30
Parallel Session 1: CRISPR for re-engineering cellular systems
Van Rysselberghezaal

Chair: Nico Callewaert

Parallel Science Session
13:45 - 14:10
Epigenome Editing with ZFP and CRISPR
Qingzhou Ji
Principal Scientist, MilliporeSigma, A business of Merck KGaA, Darmstadt, DE
Company speaker
14:10 - 14:45
In vivo genome editing with CRISPR-Cas9
Randall Platt (Group of Feng Zhang)
Broad Institute of MIT and Harvard, US
Academic speaker
14:45 - 14:50
Sponsor Talk: New Tools for Successful CRISPR/Cas9 Genome Editing
Cornelia Hampe
Product Manager Genome Editing, Westberg/ Takara/ Clontech, FR
Company speaker
14:55 - 15:00
Sponsor Talk: Ultra-Sensitive Quantification of Genome Editing Events using Droplet Digital PCR
Koen De Gelas
qPCR and ddPCR Sales Specialist, Bio-Rad
Company speaker
15:00 - 15:35
Expanding the repertoire of genetic techniques to study Protocadherin receptor diversity in X. tropicalis
Dietmar Schmucker
VIB Vesalius Research Center, KU Leuven
Academic speaker
15:35 - 16:00
New technologies for expanding ES cell-based gene targeting
Marvin Y. Ouyang
Vice President, Technologies, Cyagen Biosciences Inc.
Company speaker
16:00 - 16:30
Coffee Break
13:45 - 16:30
Parallel Session 2: Future CRISPR applications
Jan Van Eyckzaal

Chair: Sven Eyckerman

13:45 - 14:10
Studying and fighting pathogenic Bacteria with the help of CRISPR
David Bikard
Head of the Synthetic Biology Group Institut Pasteur & the CSO of Eligo Biosciences, FR
Company speaker
14:10 - 14:45
Live-cell super-resolution microscopy on genome-edited mammalian cells
Stefan Jakobs
Max Planck Institute for Biophysical Chemistry, DE
Academic speaker
14:45 - 14:50
Sponsor Talk: Geneious, a short and CRISPRy introduction to a powerful and comprehensive suite of molecular biology tools for exactly your computer
Reinhard Eckloff
VP of Sales Europe, Middle East and Africa, Geneious, DK
Company speaker
14:50 - 14:55
Sponsor Talk: Introduction to the World’s First Benchtop DNA Assembly Instrument
Justin Bingham
SGI-DNA, USA
Company speaker
14:55 - 15:00
Sponsor Talk: Automated Solutions for Genome Engineering
Frank van der Loop
Sales Specialist, Lab Services, NL
Company speaker
15:00 - 15:25
Genome Editing - We Do Delivery
Hanne Volpin
Danziger Innovations, IL
Company speaker
Watch the video of this talk
Hanne Volpin, Danziger Innovations, IL
15:25 - 16:00
In vivo and ex vivo editing using CRISPR/Cas system an emerging platform for in vivo functional genomics and gene therapy
Thierry Vandendriessche
University of Brussels (VUB), BE
Academic speaker
16:10 - 16:30
Coffee Break
16:30 - 18:05
Plenary Session: Genetic Circuits and Genome Regulation
Van Rysselberghezaal

Chair: Halina Novak

16:30 - 17:05
Expanding the targeting range and improving the genome-wide specificities of CRISPR-Cas9 nucleases
Benjamin P. Kleinstiver
Harvard Medical School, US
Academic speaker
17:05 - 17:30
The use of TALENs for crop improvement
Dan Voytas
CSO, Calyxt, US
Company speaker
17:30 - 18:05
Massively Parallel Combinatorial Genetics
Academic speaker
18:05 - 19:00
Meet the Expert: Timothy K. Lu
Van Rysselberghezaal
18:05 - 19:00
Reception
Minneplein

The program is elaborated by the members of the organizing committee:

Halina Novak, PhD, VIB Life Sciences Technology Specialist
Mark Veugelers, PhD, VIB Senior Science Policy Manager
Prof. Nico Callewaert, PhD, VIB-UGent Medical Biotechnology Center director
Prof. Sven Eyckerman, PhD, Expert Technologist, VIB Medical Biotechnology Center
Prof. Dietmar Schmucker, PhD, Group Leader, VIB Neuronal Wiring Lab
Evy Vierstraete, PhD, VIB Science Events Executive

Day 2 - 29 January 2016

Friday, 29 January, 2016
09:15 - 12:20
Plenary Session: CRISPR and SynBio Tools
Van Rysselberghezaal

Chair: Mark Veugelers

09:15 - 09:50
High-throughput biallelic modification of human iPS cells
Bill Skarnes
Wellcome Trust Sanger Institute, UK
Academic speaker
09:50 - 10:15
Genetically Modified Lactococcus lactis for Precision Intervention in the GI Tract, now Re-Wired for Target Validation
Lothar Steidler
Vice President, Intrexon Actobiotics NV, BE
Company speaker
10:15 - 10:50
Nanotechnology- and biology-based technologies for multigene editing
James Dahlman
MIT, US
Academic speaker
Watch the video of this talk
James Dahlman, MIT, US
10:50 - 11:20
Coffee Break
11:20 - 11:45
Building scale and keeping flexibility in an organism engineering foundry
Narendra Maheshri
Organism Engineer, Ginkgo Bioworks, US
Company speaker
11:45 - 12:20
Structural and mechanistic insights into RNA-guided genome editing using CRISPR-Cas9
Academic speaker
Watch the video of this talk
Martin Jinek, UZH, CH
12:20 - 13:00
Lunch
Minneplein
13:00 - 14:00
Poster Session sponsored by Twist Bioscience
Hallway & Minneplein

Twist Bioscience

14:00 - 16:30
Parallel Session 3: Expanding the Genetic Code
Van Rysselberghezaal

Chair: Halina Novak

Parallel Science Session
14:00 - 14:35
A semi-synthetic organism with an expanded genetic alphabet
Floyd Romesberg
The Scripps Research Institute, US
Academic speaker
Watch the video of this talk
Floyd E. Romesberg, Scripps Institute, US
14:35 - 15:00
Building a Synthetic Biology Company: From Academic Success to Commercial Impact
Court Turner
CEO, Synthorx, USA
Company speaker
Watch the video of this talk
Court Turner, CEO, Synthorx Inc, US
15:00 - 15:35
Expanding Biological Function with Genomically Recoded Organisms
Farren Isaacs
Yale University, USA
Academic speaker
15:35 - 16:00
Harnessing Evolution to Accelerate Genome Engineering
Jay Konieczka
COO, enEvolv, US
Company speaker
16:00 - 16:30
Coffee Break
14:00 - 16:30
Parallel Session 4: CRISPR Applications and Synthetic Biology
Jan Van Eyckzaal

Chair: Dietmar Schmucker

Parallel Science Session
14:00 - 14:35
From Mind to Molecule - Get ideas for advanced DNA designs out of your head and into your hands
Michael Fero
CEO, Teselagen, US
Company speaker
Watch the video of this talk
Michael Fero, CEO, Teselagen
14:35 - 15:00
Optimising CRISPR genome editing using machine learning technologies
Riley Doyle
CEO and Technical Lead, Desktop Genetics, UK
Company speaker
Watch the video of this talk
Riley Doyle, CEO, Desktop Genetics, UK
15:00 - 15:35
Precision Gene editing in Non-Human Primates: Approach to Establishing Human Disease Models
Weizhi Ji
The Yunnan Key Laboratory of Primate Biomedical Research, CN
Academic speaker
15:35 - 16:00
Optimized, chemically-modified crRNA:tracrRNA complexes for CRISPR gene editing
Mark Behlke
CSO, Integrated DNA Technologies, US
Company speaker
Watch the video of this talk
Mark Behlke, CSO, IDT, US
16:00 - 16:30
Coffee Break
16:30 - 18:05
Plenary Session: Targeted Genome Engineering and Design
Van Rysselberghezaal

Chair: Mark Veugelers

16:30 - 17:05
Programming biological operating systems: genome design, assembly and activation
Dan Gibson
J. Craig Venter Institute, US
Academic speaker
17:05 - 17:30
Lessons Learned from Hundreds of Individual Genome Engineering Events
Tom Henley
Associate Director of R&D, Horizon Discovery PLC, UK
Company speaker
17:30 - 18:05
Genome and Epigenome Editiing for Gene Therapy and Programming Cell Phenotype
Charles A. Gersbach
Duke University, US
Academic speaker
18:05 - 18:15
Closing
Both presentation rooms

The program is elaborated by the members of the organizing committee:

Halina Novak, PhD, VIB Life Sciences Technology Specialist
Mark Veugelers, PhD, VIB Senior Science Policy Manager
Prof. Nico Callewaert, PhD, VIB-UGent Medical Biotechnology Center director
Prof. Sven Eyckerman, PhD, Expert Technologist, VIB Medical Biotechnology Center
Prof. Dietmar Schmucker, PhD, Group Leader, VIB Neuronal Wiring Lab
Evy Vierstraete, PhD, VIB Science Events Executive