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Part of the conference series

The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)

10-11 OCTOBER 2019, LEUVEN, BELGIUM
Campaign image - The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)
Grote Markt - Leuven
Grote Markt - Leuven
Totem by Jan Fabre - Leuven
Totem by Jan Fabre - Leuven
Jubileumzaal - Venue picture
Old Market - Leuven
Old Market - Leuven
Leuven train station (copyright Bernard Hermant)
Leuven train station (copyright Bernard Hermant)
Het Pant conference room - Ghent
Het Pant conference room - Ghent
Martelaren Square - Leuven (Copyright Tobias - Cornille)
Martelaren Square - Leuven (Copyright Tobias - Cornille)
Faculty Club - Leuven
The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)

For the abstract - and attendee list, please visit the former Brain Mosaic website here.

Recent advances in technology now allow us to explore multiple aspects of heterogeneity at the single cell level. Nowhere is this more important than in the Central Nervous System (CNS), where cellular heterogeneity has profound effects on all aspects of normal brain function and behavior and explains important aspects of disease pathology.

With the second edition of the Brain Mosaic conference we aim to bring together leaders in this emerging discipline to discuss how it is advancing our knowledge of CNS function and disease. Speakers at this neuroscience meeting on ‘single cell’ will emphasize the multi-disciplinary nature of the field in several sessions:

  • Single cell sequencing and cell diversity
  • Spatial transcriptomics
  • New developments in technology and bioinformatics
  • CNS disease
  • Connections and activity


Poster prize awarded by FEBS Letters. FEBS Letters awards poster prizes to provide recognition to young scientists for their outstanding research work.

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Confirmed speakers

Program

Day 1 - Thursday, 10 October, 2019

08:30
09:00
Registration & Coffee
09:00
09:05
Welcome
09:05
12:45
Plenary session 1: Single cell sequencing and cell diversity

Chair: Carlo Sala Frigerio

09:05
09:55
Human brain development from single-cell transcriptomes
09:55
10:30
Single-cell multi-omics of the Drosophila brain and retina

Stein Aerts

VIB-KU Leuven Center for Brain & Disease Research, BE
10:30
11:00
Coffee break
11:00
11:35
Heterogeneity of Drosophila Dopaminergic Neurons
11:35
12:10
Cell types of adult mouse cortex and hippocampus
12:10
12:45
Reconstructing great ape cerebral organoids development using single-cell genomics
12:45
13:30
Lunch
13:30
14:30
Poster session
14:30
16:45
Plenary session 2: Spatial transcriptomics

Chair: Stein Aerts

14:30
15:05
Spatial data driven transcriptomics analysis of brain and neurological disease
15:05
15:40
Integrative single-cell RNA and chromatin analysis of human brain
15:40
16:15
In situ RNA sequencing reveals RNA-protein binding with sub-cellular resolution
16:15
16:40
A spatial atlas of inhibitory cell types in mouse hippocampus CA1
16:40
16:45
Sponsored talk: Quantifying gene expression in space
Sponsored talk
16:45
17:15
Coffee break
17:15
18:25
Plenary session 3: New developments in technology

Chair: Sebastian Munck

17:15
17:50
Comprehensive integration of single cell data
17:50
18:25
An integrated omics approach provides a detailed view on the molecular landscape of the brain

Jan Mulder

Department of Neuroscience, Karolinska Institutet, SE
18:25
19:00
Reception
19:00
20:00
Social program
20:00
22:30
Conference dinner

Day 2 - Friday, 11 October, 2019

08:30
09:00
Coffee
09:00
12:20
Plenary session 4: CNS disease 1

Chairs: Roosmarijn Vandenbroucke & Carlo Sala Frigerio

09:00
09:50
The power of ONE: Immunology in the age of single cell genomics
Keynote speaker
09:50
10:25
Genomic mosaicism in the normal and Alzheimer’s disease brain

Jerold Chun

Sanford Burnham Prebys Medical Discovery Institute, US
10:25
10:55
Coffee break
10:55
11:30
Single-cell transcriptomic analysis of Alzheimer’s disease

Hansruedi Mathys

Picower Institute for Learning and Memory, Massachusetts Institute of Technology, US
11:30
12:05
Somatic mutations in synucleinopathies (Parkinson’s disease and Multiple System Atrophy)
12:05
12:20
Selected Talk: A human single cell atlas of the substantia nigra reveals novel cell specific pathways associated with the genetic risks of Parkinson’s disease
12:20
13:15
Lunch
13:15
14:15
Poster session
14:15
15:05
CNS disease 2

Chairs: Roosmarijn Vandenbroucke & Carlo Sala Frigerio

14:15
14:50
Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease

Ashley Lu

VIB-KU Leuven Center for Brain & Disease Research, BE
14:50
15:05
Selected Talk: Mass cytometry analysis of aging brain in the context of cognitive decline
15:05
15:35
Coffee break
15:35
17:35
Plenary session 5: Connections and Activity

Chair: Aya Takeoka

15:35
16:10
The Janelia MouseLight Project: A platform for brain-wide reconstructions and molecular characterization of individual neurons in the mouse brain
16:10
16:25
Selected Talk: Ventral tegmental area somatostatin-expressing neuron subtypes revealed by PatchSeq method
16:25
17:00
Neuronal circuits of thermal perception
17:00
17:35
Towards a brain architecture for visual behavior selection
17:35
17:45
Closing remarks

Organizing committee

Abstracts

The full list of abstracts will be available on 01-10-2019 until 24-10-2019
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 01-10-2019 until 24-10-2019
This list will only be available for registered attendees of the event.