Part of the conference series
The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)
10-11 October 2019, Leuven, Belgium
The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)
The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)
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Bart De Strooper
Carlo Sala Frigerio
Sebastian Munck
Stein Aerts
Aya Takeoka
Roosmarijn Vandenbroucke
Evy Vierstraete
For the abstract - and attendee list, please visit the former Brain Mosaic website here.
Recent advances in technology now allow us to explore multiple aspects of heterogeneity at the single cell level. Nowhere is this more important than in the Central Nervous System (CNS), where cellular heterogeneity has profound effects on all aspects of normal brain function and behavior and explains important aspects of disease pathology.
With the second edition of the Brain Mosaic conference we aim to bring together leaders in this emerging discipline to discuss how it is advancing our knowledge of CNS function and disease. Speakers at this neuroscience meeting on ‘single cell’ will emphasize the multi-disciplinary nature of the field in several sessions:
- Single cell sequencing and cell diversity
- Spatial transcriptomics
- New developments in technology and bioinformatics
- CNS disease
- Connections and activity
Poster prize awarded by FEBS Letters. FEBS Letters awards poster prizes to provide recognition to young scientists for their outstanding research work.
Confirmed speakers
Barbara Treutlein
Barbara Treutlein
ETH Zürich, Department of Biosystems Science and Engineering (D-BSSE), CH
Hansruedi Mathys
Hansruedi Mathys
Picower Institute for Learning and Memory, Massachusetts Institute of Technology, US
Christos Proukakis
Christos Proukakis
UCL Queen Square Institute of Neurology, University College London, UK
Program
Day 1 - Thursday, 10 October, 2019
08:30
09:00
Registration & Coffee
09:00
09:05
Welcome
09:05
12:45
Plenary session 1: Single cell sequencing and cell diversity
Chair: Carlo Sala Frigerio
09:05
09:55
Human brain development from single-cell transcriptomes
Sten Linnarsson
Karolinska Institute, SE
Keynote speaker
09:55
10:30
Single-cell multi-omics of the Drosophila brain and retina
Stein Aerts
VIB Center for AI & Computational Biology, BE
10:30
11:00
Coffee break
11:00
11:35
Heterogeneity of Drosophila Dopaminergic Neurons
Scott Waddell
University of Oxford, UK
11:35
12:10
Cell types of adult mouse cortex and hippocampus
Bosiljka Tasic
Allen Institute for Brain Science, US
12:10
12:45
Reconstructing great ape cerebral organoids development using single-cell genomics
Barbara Treutlein
ETH Zürich, Department of Biosystems Science and Engineering (D-BSSE), CH
12:45
13:30
Lunch
13:30
14:30
Poster session
14:30
16:45
Plenary session 2: Spatial transcriptomics
Chair: Stein Aerts
14:30
15:05
Spatial data driven transcriptomics analysis of brain and neurological disease
Joakim Lundeberg
SciLifeLab, KTH Royal Institute of Technology, SE
15:05
15:40
Integrative single-cell RNA and chromatin analysis of human brain
Kun Zhang
University of California, US
15:40
16:15
In situ RNA sequencing reveals RNA-protein binding with sub-cellular resolution
Je Hyuk Lee
Cold Spring Harbor Laboratory, US
16:15
16:40
A spatial atlas of inhibitory cell types in mouse hippocampus CA1
Xiaoyan Qian
Stockholm University, SE & Cartana, SE
16:40
16:45
Sponsored talk: Quantifying gene expression in space
Sponsored talk
Christian Korfhage
Qiagen, DE
Sponsored talk
16:45
17:15
Coffee break
17:15
18:25
Plenary session 3: New developments in technology
Chair: Sebastian Munck
17:15
17:50
Comprehensive integration of single cell data
Rahul Satija
New York Genome Center & NYU, US
17:50
18:25
An integrated omics approach provides a detailed view on the molecular landscape of the brain
Jan Mulder
Department of Neuroscience, Karolinska Institutet, SE
18:25
19:00
Reception
19:00
20:00
Social program
20:00
22:30
Conference dinner
Day 2 - Friday, 11 October, 2019
08:30
09:00
Coffee
09:00
12:20
Plenary session 4: CNS disease 1
Chairs: Roosmarijn Vandenbroucke & Carlo Sala Frigerio
09:00
09:50
The power of ONE: Immunology in the age of single cell genomics
Ido Amit
Weizmann Institute of Science, IL
Keynote speaker
09:50
10:25
Genomic mosaicism in the normal and Alzheimer’s disease brain
Jerold Chun
Sanford Burnham Prebys Medical Discovery Institute, US
10:25
10:55
Coffee break
10:55
11:30
Single-cell transcriptomic analysis of Alzheimer’s disease
Hansruedi Mathys
Picower Institute for Learning and Memory, Massachusetts Institute of Technology, US
11:30
12:05
Somatic mutations in synucleinopathies (Parkinson’s disease and Multiple System Atrophy)
Christos Proukakis
UCL Queen Square Institute of Neurology, University College London, UK
12:05
12:20
Selected Talk: A human single cell atlas of the substantia nigra reveals novel cell specific pathways associated with the genetic risks of Parkinson’s disease
Viola Volpato
Cardiff University, UK
Selected from abstracts
12:20
13:15
Lunch
13:15
14:15
Poster session
14:15
15:05
CNS disease 2
Chairs: Roosmarijn Vandenbroucke & Carlo Sala Frigerio
14:15
14:50
Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease
Wei-Ting Chen
VIB-KU Leuven Center for Brain & Disease Research, BE
14:50
15:05
Selected Talk: Mass cytometry analysis of aging brain in the context of cognitive decline
Marissa Schafer
Mayo Clinic, US
Selected from abstracts
15:05
15:35
Coffee break
15:35
17:35
Plenary session 5: Connections and Activity
Chair: Aya Takeoka
15:35
16:10
The Janelia MouseLight Project: A platform for brain-wide reconstructions and molecular characterization of individual neurons in the mouse brain
Jayaram Chandrashekar
HHMI Janelia Research Campus, US
16:10
16:25
Selected Talk: Ventral tegmental area somatostatin-expressing neuron subtypes revealed by PatchSeq method
Elina Nagaeva
University of Helsinki, FI
Selected from abstracts
16:25
17:00
Neuronal circuits of thermal perception
James Poulet
Max Delbrück Center (MDC), DE
17:00
17:35
Towards a brain architecture for visual behavior selection
Gwyneth Card
HHMI Janelia Research Campus, US
17:35
17:45
Closing remarks
Organizing committee
Bart De Strooper
VIB-KU Leuven Center for Brain & Disease Research, BE & UK Dementia Research Institute, UK
Carlo Sala Frigerio
UK Dementia Research Institute, UK
Sebastian Munck
VIB Bioimaging Core KULeuven, BE
Stein Aerts
VIB Center for AI & Computational Biology, BE
Aya Takeoka
NERF, empowered by IMEC, KU Leuven and VIB, BE
Roosmarijn Vandenbroucke
VIB-UGent Center for Inflammation Research, BE
Evy Vierstraete
VIB Headquarters, BE
Abstracts
The full list of abstracts will be available on 01-10-2019 until 24-10-2019
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Attendees
The full list of attendees will be available on 01-10-2019 until 24-10-2019
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Sponsors
Silver
Silver
Silver
