Next-Generation Antibodies and Protein Analysis: Tools and Technologies

15-16 JUNE 2015, GENT, BELGIUM
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Next-Generation Antibodies and Protein Analysis: Tools and Technologies

VIB’s Tools and Technologies meetings provide a forum for top academic speakers and scientists from both established and emerging companies to present their latest scientific achievements and exciting technological solutions. The Next-Generation Antibodies and Protein Analysis conference will look at emerging tools and approaches in the field of Comprehensive Proteomics, Protein Modifications, Single Domain and Recombinant Antibody tools, Next-Generation Affinity Reagents, Interactomics, Protein Sensing and Molecular Interactions, Single Molecule Analysis and Single-Cell Proteome Analysis.

Catalyzed by VIB’s Technology Scouting team, the Tools and Technologies meetings focus on the front end of innovation and bring together key innovators in selected life sciences research fields. Past and upcoming meetings in the Tools and Technologies series (Genome Engineering and Synthetic biology, September 2013 and Next-Generation Sequencing, January 2015) have proven a tremendous success.

The Next-Generation Antibodies and Protein Analysis conference is set to make another world class meeting, bringing together an exciting selection of top speakers (having published more then 400+ top papers in Nature, Cell and Science) and newly emerged companies. In addition to great scientific and technology program, the conference will provide ample networking opportunities.

Top speakers: 

David C. Duffy

CTO, Quanterix Corporation, US

Ruedi Aebersold

ETH, Zurich, CH

Igor Stagljar

Donnelly Centre, the University of Toronto, CA

Stephen Elledge

Harvard Medical School, US and Howard Hughes Medical Institute, US

Paul Ko Ferrigno

CSO, Avacta Life Sciences, UK

Akos Vertes

George Washington University in Washington, US

Hagan Bayley

University of Oxford, UK

Liangcai Gu

Harvard Medical School, US

Mark Vaeck

CEO, Complix NV, BE

Bernhard Küster

Technical University Munich, DE

Francois Vigneault

President, CSO & Founder, AbVitro Inc., US

Ichiro Hirao

RIKEN Center for Life Science Technologies & TagCyx Biotechnologies, JP

Jonathan Tang

Harvard Medical School, US

Frank Becker

Intana Bioscience GmbH, DE

Frank F. Craig

CEO, Sphere Fluidics Limited, UK

Jim Freeth

Managing Director, Retrogenix, UK

Michael Weiner

CSO, AxioMx, US

Paola Picotti

ETH Zurich, CH

Steven Carr

Broad Institute of MIT and Harvard, US

Vaughn Smider

Scripps Research Institute, US

Allan Jensen

CSO, HiFiBio, FR

Bradley Messmer

Founder, Abreos Biosciences, US

J. Christopher Love

MIT & Harvard, US

Darryl J. Bornhop

Vanderbilt University, US

Jan Steyaert

VIB Structural Biology Research Center, VUB, BE

Philipp Baaske

CEO, NanoTemper Technologies GmbH, DE

Sriram Kumaraswamy

Senior Director, Pall ForteBio LLC, US

Ulrich Rant

CEO, Dynamic Biosensors, DE

Vladislav Bergo

CSO, Adeptrix, US

Christopher M. Overall

University British Columbia, CA

Olga Ornatsky

Principle Scientist and Co-founder of DVS Sciences, Fluidigm, US

Deepa Shankar

R&D Director, Thermo Fisher Scientific (Life Technologies), US

Nebojsa Janjic

CSO, Somalogic, US

Floris van Delft

CSO, SynAffix, NL

Hans Vissers

Senior Manager Science Operations, Waters Corporation, UK

Xun Meng

CEO, Ab-Mart, CN

Anne-Claude Gingras

The Lunenfeld-Tanenbaum Research Institute, CA

Kris Gevaert

VIB Department of Medical Protein Research, UGent

Nick Morrice

Senior Specialist Support Proteomics, SCIEX, UK

Sebastian J. Maerkl

École Polytechnique Fédérale de Lausanne, CH

John Thornback

Managing Director, Apta Biosciences, UK

Mike Taussig

CEO, Cambridge Protein Arrays, UK

Rong Fan

Yale University, US
Download the program: 

Monday, 15 June, 2015

Monday, 15 June, 2015
08:45 - 09:15
Coffee/Registration
09:15 - 12:45
Morning Parallel session 1: Comprehensive Proteomics
09:15 - 09:20
Welcome
Mark Veugelers
VIB Headquarters
09:20 - 09:50
Protein conformational changes in health and disease
Paola Picotti
ETH Zurich, CH
Academic speaker
Watch the video of this talk
Paola Picotti, ETH Zurich, CH
09:50 - 10:20
What I talk about when I talk about protein N-termini
Kris Gevaert
VIB Department of Medical Protein Research, UGent
Academic speaker
10:20 - 10:25
Short Sponsors Talk: Using monoisotopic mass of antibody sub units to determine sequence and deamidation
Frank Aerts
Bruker
Company speaker
10:25 - 10:30
Short Sponsors Talk: Automated Small Scale Protein Purification and Characterization for Accelerated Development of Protein Therapeutics
Nico Verlinden
PerkinElmer
Company speaker
10:30 - 10:35
Short Sponsor Talk: Standardized protein quantification using a novel micro-volume platform with spectral content profiling
Tony Montoye
Head of Marketing and Applications, Trinean, Belgium
Academic speaker
10:40 - 11:05
Systematic Comparison of Integrated Microfluidics/Nanoscale LC Platforms and High/Low Resolution Mass Spectrometers for Quantitative MRM Analysis of Candidate Protein Biomarkers
Hans Vissers
Senior Manager Science Operations, Waters Corporation, UK
Company speaker
11:00 - 11:30
Coffee Break
11:30 - 11:55
Microflow LC-MSMS on TripleTOF Mass Spectrometry Systems for Proteomic Applications
Nick Morrice
Senior Specialist Support Proteomics, SCIEX, UK
Company speaker
11:55 - 12:00
Short sponsor talk: Advances in Antibody-based Proteomic Analysis in Biomarker Discovery
Edward Verwayen
Cell Signaling Technology
Company speaker
12:00 - 12:05
Short sponsor talk: Nanobody tools: Nanobody tools: Elevated level proteomics & cellular analysis
Marion Jung
Chromotek
Company speaker
12:05 - 12:10
Short sponsor talk: Electrochemical Reduction of Disulphide Bonds for Superior Characterisation of Protein Therapeutics by MS
Laurent Rieux
Antec
Company speaker
12:15 - 12:45
Human Proteomes – From Basic Science to Understanding Drug Action
Bernhard Küster
Technical University Munich, DE
Academic speaker
09:15 - 12:50
Morning Parallel Session 2: Single Domain and Recombinant Antibody tools
Parallel Science Session
09:15 - 09:20
Welcome
Halina Novak
VIB Headquarters
09:20 - 09:50
Innovative Access Program for Academic Groups: ARGX-115
Michael Saunders
Argen-X
Company speaker
Watch the video of this talk
Michael Saunders, Argen-X
09:50 - 10:15
Affimers: Engineered Affinity Protein Alternatives to Antibodies
Paul Ko Ferrigno
CSO, Avacta Life Sciences, UK
Company speaker
10:15 - 10:20
Short sponsor talk: Recombinant Antibodies for the Research Market
Nicholas Hutchings
Absolute Antibody
Company speaker
10:20 - 10:25
Short sponsor talk: Antibody tailoring for success: the journey and services around
Daniela Teixeira
Fair Journey Biologics
Company speaker
10:25 - 10:30
Short sponsor talk: Introduction to Abcam
Diane De Pastre
Abcam
Company speaker
10:35 - 11:00
Ultra-Rapid Production of Recombinant IgG Affinity Reagents
Michael Weiner
CSO, AxioMx, US
Company speaker
Watch the video of this talk
Michael Weiner, CSO, AxioMx, US
11:00 - 11:30
Coffee Break
11:30 - 12:00
Co-opting fluorescent proteins for cell-specific gene manipulation
Jonathan Tang
Harvard Medical School, US
Academic speaker
Watch the video of this talk
Jonathan Tang, Harvard Medical School, US
12:00 - 12:25
Alphabodies : A novel platform for addressing intracellular therapeutic targets
Mark Vaeck
CEO, Complix NV, BE
Company speaker
12:25 - 12:50
NextGen Antibodies: Towards Achieving Scientific Reproducibility with Specificity, Sensitivity and Selectivity
Deepa Shankar
R&D Director, Thermo Fisher Scientific (Life Technologies), US
Company speaker
12:45 - 14:00
Lunch & Poster session 1 (Presenting the odd poster numbers)
14:00 - 17:35
Afternoon Parallel Session 1: Next-Generation affinity reagents
Parallel Science Session
14:00 - 14:30
Cow antibodies with long CDR3s: biology and applications
Vaughn Smider
Scripps Research Institute, US
Academic speaker
14:30 - 14:55
A massively parallel monoclonal antibody array for proteome-scale target/biomarker discovery
Xun Meng
CEO, Ab-Mart, CN
Company speaker
14:55 - 15:20
Deep Mining of Immune Repertories for Antibody Discovery
Allan Jensen
CSO, HiFiBio, FR
Company speaker
Watch the video of this talk
Allan Jensen, CSO, HiFiBio, FR
15:20 - 15:45
High Throughput sequencing of paired full-length antibody and TCR repertoires by single cell barcoding in emulsion
Francois Vigneault
President, CSO & Founder, AbVitro Inc., US
Company speaker
15:45 - 16:15
Coffee Break
16:15 - 16:45
High Affinity DNA Aptamers by a genetic alphabet expansion as an antibody drug candidate
Ichiro Hirao
RIKEN Center for Life Science Technologies & TagCyx Biotechnologies, JP
Academic speaker
16:45 - 17:10
From front-loading to affinity maturation. Finding optimal modifications on nucleic acid ligands
Nebojsa Janjic
CSO, Somalogic, US
Company speaker
Watch the video of this talk
Nebojsa Janjic, CSO, Somalogic, US
17:10 - 17:35
SELIGO: A New Customisable Class of Affinity Regents.
John Thornback
Managing Director, Apta Biosciences, UK
Company speaker
14:00 - 17:35
Afternoon Parallel Session 2: Interactomics
Parallel Science Session
14:00 - 14:30
A physical map of a human cell
Anne-Claude Gingras
The Lunenfeld-Tanenbaum Research Institute, CA
Academic speaker
14:30 - 14:35
Short sponsor talk: Lambda RIDe: A novel label-free detection method for kinetic analysis of protein microarrays
Frank Schleifenbaum
Berthold Technologies
Company speaker
14:35 - 14:40
Short sponsor talk: Efficient “pre-clinical” manufacturing for successful biologics development
Marc Daukandt
Xpress Biologics
Company speaker
14:40 - 14:45
Short sponsor talk: Using Microcalorimetry to Characterize Biomolecular Interactions
Eva-Karin Jyde
Malvern
Company speaker
14:50 - 15:20
Membrane Protein Interactomes in Health & Disease: application to lung cancer
Igor Stagljar
Donnelly Centre, the University of Toronto, CA
Academic speaker
15:20 - 15:45
Proteome-wide Protein Microarrays: Technologies and Applications
Mike Taussig
CEO, Cambridge Protein Arrays, UK
15:45 - 16:15
Coffee Break
16:15 - 16:45
Comprehensive serological profiling of human populations using a synthetic human virome
Stephen Elledge
Harvard Medical School, US and Howard Hughes Medical Institute, US
Academic speaker
16:45 - 16:50
Short sponsor talk: TruBind™ BSI Technology: Accelerating Drug Discovery in Allostery and Membrane Target Research
Scot R. Weinberger
Molecular Sensing
Company speaker
16:50 - 16:55
Short sponsor talk: Antibodies for in-vivo systems
Company speaker
16:55 - 17:00
Short sponsor talk: EVALUTION™: The new multiplexing solution for your biomarkers
Joseph She
MyCartis
Company speaker
17:05 - 17:30
Uncovering Primary and Secondary Targets for Antibodies and Protein Ligands using Cell Microarray Technology
Jim Freeth
Managing Director, Retrogenix, UK
Company speaker
17:35 - 18:30
Closing Drink

Members of the NGAPA organizing committee:
Halina Novak, PhD, VIB Life Sciences Technology Specialist
Mark Veugelers, PhD, VIB Senior Science Policy Manager
Kris Gevaert, PhD, VIB Professor in Functional Proteomics
Han Remaut, PhD, VIB Professor in Structural Biology
Evy Vierstraete, PhD, VIB Science Events Executive

Tuesday, 16 June, 2015

Tuesday, 16 June, 2015
09:30 - 12:30
Morning Parallel Session 1: Protein modifications
Parallel Science Session
09:30 - 10:00
Quantification of post translational modifications by SWATH mass Spectometry
Ruedi Aebersold
ETH, Zurich, CH
Academic speaker
Watch the video of this talk
Ruedi Aebersold, ETH Zurich, CH
10:00 - 10:25
GlycoConnect™ and HydraSpace™ Enable a Non-Genetic Entry into Homogeneous ADCs with Improved Stability
Floris van Delft
CSO, SynAffix, NL
Company speaker
10:25 - 10:50
BAMS: a dual mass spectrometry and fluorescence microarray platform for proteomics
Vladislav Bergo
CSO, Adeptrix, US
Company speaker
Watch the video of this talk
Vladislav Bergo, CSO, Adeptrix, US
11:00 - 11:30
Coffee Break
11:30 - 12:00
Protein TAILS tell remarkable tales
Christopher M. Overall
University British Columbia, CA
Academic speaker
12:00 - 12:30
Quantitative Proteomics in Biology, Chemistry and Medicine
Steven Carr
Broad Institute of MIT and Harvard, US
Academic speaker
09:30 - 12:25
Morning Parallel Session 2: Protein sensing, expression and molecular interactions
Parallel Science Session
09:30 - 10:00
Quantifying Molecular Interactions in Complex Milieu at Zeptomole Sensitivity without Labels or Tethering
Darryl J. Bornhop
Vanderbilt University, US
Academic speaker
10:00 - 10:25
MicroScale Thermophoresis & Molecular Interactions: A Love Story
Philipp Baaske
CEO, NanoTemper Technologies GmbH, DE
Company speaker
10:25 - 10:50
Label-free Binding Assays in the Processing and Analysis of Biopharmaceuticals
Sriram Kumaraswamy
Senior Director, Pall ForteBio LLC, US
Company speaker
11:00 - 11:30
Coffee Break
11:30 - 12:00
Rapid Protein Engineering
Sebastian J. Maerkl
École Polytechnique Fédérale de Lausanne, CH
Academic speaker
12:00 - 12:25
Biophysical analysis of molecular interactions with electro-switchable biosurfaces
Ulrich Rant
CEO, Dynamic Biosensors, DE
Company speaker
Watch the video of this talk
Ulrich Rant, CEO, Dynamic Biosensors, DE
12:30 - 14:00
Lunch & Poster session 2 (Presenting the even poster numbers)
14:00 - 16:00
Afternoon Parallel Session 1A: Single-Molecule Bio-sensing
Parallel Science Session
14:00 - 14:30
Analyzing single biomacromolecules with nanopores
Hagan Bayley
University of Oxford, UK
Academic speaker
Watch the video of this talk
Hagan Bayley, University of Oxford, UK
14:30 - 14:55
The Simoa HD-1 Analyzer: a fully-automated, multiplexed immunoanalyzer with single molecule sensitivity
David C. Duffy
CTO, Quanterix Corporation, US
Company speaker
14:55 - 15:20
Application of FCCS to analyze the affinity and kinetic parameters of ligands to the CXCR4 receptor
Manal Chatila
Business Development representative, Intana Bioscience GmbH, DE
Company speaker
15:25 - 16:00
Coffee Break
16:00 - 16:55
Afternoon Parallel Session 1B: Multiplexing Protein Detection
Parallel Science Session
16:00 - 16:30
In Situ Sequencing of Protein Interactomes
Liangcai Gu
Harvard Medical School, US
Academic speaker
Watch the video of this talk
Liangcai Gu, Harvard Medical School, US
16:30 - 16:55
Biomimetic avidity reagents for antibody and protein detection
Bradley Messmer
Founder, Abreos Biosciences, US
Company speaker
14:00 - 16:55
Afternoon Parallel Session 2: Single-Cell Proteome Analysis
14:00 - 14:30
Single-Cell, Hi-Plex Immune Function Analysis for Measuring Protective Response or Pathogenesis
Rong Fan
Yale University, US
Academic speaker
14:30 - 15:00
Metabolic Diversity, Response and Turnover Followed in Single Cells
Akos Vertes
George Washington University in Washington, US
Academic speaker
15:00 - 15:25
Mass Cytometry for Massively Multiparametric Protein Assay in Single-Cell Suspension and Tissue Imaging
Olga Ornatsky
Principle Scientist and Co-founder of DVS Sciences, Fluidigm, US
Company speaker
15:25 - 16:00
Coffee Break
16:00 - 16:30
Tools for rapid discovery and production of antibodies
J. Christopher Love
MIT & Harvard, US
Academic speaker
16:30 - 16:55
The Cyto-Mine™ Single Cell Analysis Platform for Accelerated Biopharmaceutical Discovery and Development
Frank F. Craig
CEO, Sphere Fluidics Limited, UK
Company speaker
16:55 - 17:10
Closing remarks

Members of the NGAPA organizing committee:
Halina Novak, PhD, VIB Life Sciences Technology Specialist
Mark Veugelers, PhD, VIB Senior Science Policy Manager
Kris Gevaert, PhD, VIB Professor in Functional Proteomics
Han Remaut, PhD, VIB Professor in Structural Biology
Evy Vierstraete, PhD, VIB Science Events Executive