Cell-VIB Symposium: Hallmarks of Cancer
11-13 December 2016, Ghent, Belgium
Cell-VIB Symposium: Hallmarks of Cancer
Organized by Cell Symposia & VIB Conferences
As one of the most investigated areas in biomedical research, the cancer field is rapidly advancing by translating biological insights towards better detection and therapeutics, including molecular classifications as well as immunotherapies. In the era of the genetically informed, emerging concepts in cancer biology and oncology research are colliding into precision medicine. In order to accelerate the development of personalized cancer therapies and further translate fundamental discoveries into the clinic, there must be open lines of communication at the interface between the lab and the clinic.
Our goal in organizing this Cell Symposium, Hallmarks of Cancer, is to convene global leaders in the cancer research arena to enhance our understanding of the key aspects of cancer and how to promote translation of this knowledge into the development of more effective therapeutics. We aim to provide a high-impact, high-profile forum for exchanging ideas and establishing a dialogue amongst clinicians, scientists and drug development companies. Keynote speakers will be Lewis Cantley and Laurence Zitvogel.
Symposium themes:
- Tumor metabolism
- Tumor heterogeneity
- Tumor immunology and immunotherapy
- Personalized cancer therapy
- Metastasis and the tumor microenvironment
Confirmed speakers
Program
Day 1 - Sunday, 11 December, 2016
11:00
13:30
Registration
Session I: Tumor Metabolism
13:40
14:30
PI 3-Kinase and Cancer Metabolism
Lewis Cantley
Weill Cornell, US
Keynote speaker
14:30
15:00
A role for p53 in the adaptation to metabolic stress
Karen Vousden
The Francis Crick Institute, UK
15:00
15:15
Clinical proteomics of invasive breast carcinoma reveals a major role for proline metabolism in imparting drug resistance
A. Shenoy
Tel Aviv University, IL
Selected from abstracts
15:15
15:45
Refreshment Break
15:45
16:15
Metabolic heterogeneity in molecular subtypes of diffuse large B cell lymphoma
Nika Danial
Dana-Farber Cancer Institute, Harvard, US
16:15
16:45
Angiogenesis revisited: Role and (therapeutic) implications of endothelial metabolism
Peter Carmeliet
VIB-KU Leuven Center for Cancer Biology, BE
16:45
17:00
Cancer associated fibroblast focal adhesion kinase regulates tumour metabolism
F. Demircioglu
Barts Cancer Institute, UK
Selected from abstracts
17:00
17:15
Discussion
17:15
18:30
Welcome Drinks Reception
Day 2 - Monday, 12 December, 2016
Session II: Tumor Heterogeneity
08:30
09:30
Addressing immune hallmarks: Neoantigen prediction and vaccine design
Elaine Mardis
Washington University School of Medicine, US
09:00
09:30
From genomic variation to molecular mechanism
Jan Korbel
EMBL, DE
09:30
10:00
SWI/SNF (BAF) complex mutations in cancer
Charles W. M. Roberts
St. Jude Children’s Research Hospital, US
10:00
10:15
Understanding the mechanisms controlling EMT mediated resistance to therapy
M. Debaugnies
Université libre de Bruxelles, BE
Selected from abstracts
10:15
10:45
Refreshment break
10:45
11:15
TRACERx - Tracking lung cancer evolution through therapy
Charles Swanton
The Francis Crick Institute, UK
11:15
11:30
Therapeutic implications of endothelial heterogeneity and plasticity in glioma
K. Matsumoto
Vesalius Research Center, BE
Selected from abstracts
11:30
11:45
Discussion
11:45
12:30
Meet the Editors
12:30
13:30
Lunch
13:30
14:30
Poster Session I
Session III: Personalized Cancer Therapy
14:30
15:00
Multi-organ mapping of cancer risk
Richard Gilbertson
University of Cambridge, UK
15:00
15:30
Melanoma treatment: A new era of progress and challenges
Caroline Robert
Institute Gustave Roussy, FR
15:30
15:45
Fine tuning of pro-metastatic factors by RNA complexes controlled by p62/Sequestosome-1 in melanoma
P. Karras
Spanish National Cancer Research Centre (CNIO), ES
Selected from abstracts
15:45
16:15
Refreshment Break
16:15
16:45
Tumor evolution as a therapeutic target
Alberto Bardelli
University of Torino, It
16:45
17:15
Therapy of lymphoma inspired by functional and structural genomics
Louis Staudt
NIH/NCI, US
17:15
17:30
Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance
Selected from abstracts
17:30
17:45
Discussion
19:00
22:00
Meet the Speakers Dinner
Day 3 - Tuesday, 13 December, 2016
Session IV: Metastasis & Tumor Microenvironment
08:45
09:15
Deciphering mechanisms of resistance to microenvironment-targeted therapies
Johanna Joyce
UNIL/ LICR, CH
09:15
09:45
Tumor exosomes determine organotropic metastasis
David Lyden
Weill Cornell, US
09:45
10:00
Genetic reconstitution of metastatic colorectal cancer in immunocompetent mice
D.V.F. Tauriello
Institute for Research in Biomedicine Barelona, ES
Selected from abstracts
10:00
10:30
Refreshment Break
10:30
11:00
The control of epithelial plasticity and the EMT type
Angela Nieto
Instituto de Neurociencias CSIC-UMH, ES
11:00
11:30
TCYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
Andreas Trumpp
DKFZ, DE
11:30
11:45
Macrophages promote pancreatic cancer metastasis by forming a hospitable metastatic niche
M.C. Schmid
University of Liverpool, UK
Selected from abstracts
11:45
12:00
Discussion
12:00
13:00
Lunch
13:00
14:00
Poster Session II
Session V: Tumor Immunology & Immunotherapy
14:00
14:30
Padmanee Sharma
University of Texas M. D. Anderson Cancer Center, US
14:30
15:00
Jeff Pollard
Edinburgh University, UK
15:00
15:15
Ccl5 and cxcl9 chemokines cooperate to orchestrate cd8+ t-cell engraftment in tumors
D. Dangaj
Ludwig Institute for Cancer Research, CH
Selected from abstracts
15:15
15:45
Refreshment Break
15:45
16:15
T cell recognition and tumor resistance in human cancer
Ton Schumacher
Netherlands Cancer Institur/Antoni van Leeuwenhoek, NL
16:15
16:30
Checkpoint blockade immunotherapy reshapes the high-dimensional heterogeneity of intratumoral neoantigen-specific CD8+ T cells
M. Fehlings
1Agency for Science, Technology and Research (A*STAR), SG
Selected from abstracts
16:30
17:20
Cancer and Microbiota: immunity is the link
Laurence Zitvogel
Gustave Roussy, INSERM, University Paris Saclay, FR
Keynote speaker
Organizing committee
Blanpain Cédric
Laboratory of Stem Cells and Cancer, ULB
Johanna Joyce
MSKCC, US
Diether Lambrechts
VIB-KU Leuven Center for Cancer Biology, BE
Jean-Christophe Marine
VIB-KU Leuven Center for Cancer Biology, BE
Li-Kuo Su
Editor, Cancer Cell, US
Jiaying Tan
Scientific Editor, Cell, US
Abstracts
The full list of abstracts will be available on 04-12-2016 until 27-12-2016
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Attendees
The full list of attendees will be available on 04-12-2016 until 27-12-2016
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.