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Cell-VIB Symposium: Hallmarks of Cancer

11-13 December 2016, Ghent, Belgium
Cell-VIB Symposium: Hallmarks of Cancer - campaign visual
Cell-VIB Symposium: Hallmarks of Cancer

Organized by Cell Symposia & VIB Conferences

As one of the most investigated areas in biomedical research, the cancer field is rapidly advancing by translating biological insights towards better detection and therapeutics, including molecular classifications as well as immunotherapies. In the era of the genetically informed, emerging concepts in cancer biology and oncology research are colliding into precision medicine. In order to accelerate the development of personalized cancer therapies and further translate fundamental discoveries into the clinic, there must be open lines of communication at the interface between the lab and the clinic.

Our goal in organizing this Cell Symposium, Hallmarks of Cancer, is to convene global leaders in the cancer research arena to enhance our understanding of the key aspects of cancer and how to promote translation of this knowledge into the development of more effective therapeutics. We aim to provide a high-impact, high-profile forum for exchanging ideas and establishing a dialogue amongst clinicians, scientists and drug development companies. Keynote speakers will be Lewis Cantley and Laurence Zitvogel.

Symposium themes:

  • Tumor metabolism
  • Tumor heterogeneity
  • Tumor immunology and immunotherapy
  • Personalized cancer therapy
  • Metastasis and the tumor microenvironment
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Confirmed speakers

Program

Day 1 - Sunday, 11 December, 2016

11:00
13:30
Registration
Session I: Tumor Metabolism
13:40
14:30
PI 3-Kinase and Cancer Metabolism
14:30
15:00
A role for p53 in the adaptation to metabolic stress
15:00
15:15
Clinical proteomics of invasive breast carcinoma reveals a major role for proline metabolism in imparting drug resistance
Selected from abstracts
15:15
15:45
Refreshment Break
15:45
16:15
Metabolic heterogeneity in molecular subtypes of diffuse large B cell lymphoma
16:15
16:45
Angiogenesis revisited: Role and (therapeutic) implications of endothelial metabolism
16:45
17:00
Cancer associated fibroblast focal adhesion kinase regulates tumour metabolism
17:00
17:15
Discussion
17:15
18:30
Welcome Drinks Reception

Day 2 - Monday, 12 December, 2016

Session II: Tumor Heterogeneity
08:30
09:30
Addressing immune hallmarks: Neoantigen prediction and vaccine design
09:00
09:30
From genomic variation to molecular mechanism
09:30
10:00
SWI/SNF (BAF) complex mutations in cancer
10:00
10:15
Understanding the mechanisms controlling EMT mediated resistance to therapy
10:15
10:45
Refreshment break
10:45
11:15
TRACERx - Tracking lung cancer evolution through therapy
11:15
11:30
Therapeutic implications of endothelial heterogeneity and plasticity in glioma
11:30
11:45
Discussion
11:45
12:30
Meet the Editors
12:30
13:30
Lunch
13:30
14:30
Poster Session I
Session III: Personalized Cancer Therapy
15:00
15:30
Melanoma treatment: A new era of progress and challenges
15:30
15:45
Fine tuning of pro-metastatic factors by RNA complexes controlled by p62/Sequestosome-1 in melanoma

P. Karras

Spanish National Cancer Research Centre (CNIO), ES
Selected from abstracts
15:45
16:15
Refreshment Break
16:15
16:45
Tumor evolution as a therapeutic target
16:45
17:15
Therapy of lymphoma inspired by functional and structural genomics
17:15
17:30
Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance
17:30
17:45
Discussion
19:00
22:00
Meet the Speakers Dinner

Day 3 - Tuesday, 13 December, 2016

Session IV: Metastasis & Tumor Microenvironment
08:45
09:15
Deciphering mechanisms of resistance to microenvironment-targeted therapies
09:15
09:45
Tumor exosomes determine organotropic metastasis
09:45
10:00
Genetic reconstitution of metastatic colorectal cancer in immunocompetent mice
Selected from abstracts
10:00
10:30
Refreshment Break
10:30
11:00
The control of epithelial plasticity and the EMT type
11:00
11:30
TCYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
11:30
11:45
Macrophages promote pancreatic cancer metastasis by forming a hospitable metastatic niche
Selected from abstracts
11:45
12:00
Discussion
12:00
13:00
Lunch
13:00
14:00
Poster Session II
Session V: Tumor Immunology & Immunotherapy
15:00
15:15
Ccl5 and cxcl9 chemokines cooperate to orchestrate cd8+ t-cell engraftment in tumors
Selected from abstracts
15:15
15:45
Refreshment Break
15:45
16:15
T cell recognition and tumor resistance in human cancer
16:15
16:30
Checkpoint blockade immunotherapy reshapes the high-dimensional heterogeneity of intratumoral neoantigen-specific CD8+ T cells

M. Fehlings

1Agency for Science, Technology and Research (A*STAR), SG
Selected from abstracts
16:30
17:20
Cancer and Microbiota: immunity is the link

Organizing committee

Johanna Joyce

MSKCC, US

Li-Kuo Su

Editor, Cancer Cell, US

Jiaying Tan

Scientific Editor, Cell, US

Abstracts

The full list of abstracts will be available on 04-12-2016 until 27-12-2016
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 04-12-2016 until 27-12-2016
This list will only be available for registered attendees of the event.