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Metabolism in Cancer and Stromal Cells

8-10 September 2015, Leuven, Belgium
Metabolism in Cancer and Stromal Cells - campaign visual
Metabolism in Cancer and Stromal Cells
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The metabolism of cancer cells and recently also of stromal cells (endothelial cells, immune cells, fibroblasts) have emerged as critical hallmark in the (patho)physiology of organs in healthy and diseased tissue. Evidence indicates that metabolism not only co-determines the differentiation and function of cells, but it also contributes to the pathogenesis of cancer, diabetes and inflammatory diseases. With this international meeting we will focus on how cancer and stromal cells metabolically communicate and how their specific metabolism impacts disease development and progression. These insights into cellular metabolism also offer novel therapeutic opportunities for malignant, metabolic, or inflammatory disease.

This meeting will bring together researchers from cancer metabolism and stromal cell metabolism fields. Renowned speakers will provide a broad view on metabolic regulation, the link between signaling and metabolism as well as the intercellular crosstalk. This event will provide an opportunity to discuss the latest findings in those fields. These discussions will stimulate new ideas and impact the field by introducing novel concepts and experimental approaches.

This conference is organized in collaboration with Vesalius Research Center and KU Leuven.

‘Meet the Expert’ session with Dr. M. Celeste Simon
We offer all junior researchers an opportunity to join keynote speaker Dr. M. Celeste Simon in a 'Meet the Expert' session during the conference. On Thursday September 10 during the coffee break from 16:05-16:35 you will have the opportunity to ask any question/advise/feedback related to your research project/your research during an informal round table discussion. If you are interested in joining the session then send an e-mail to conferences@vib.be and let us know. Seating is very limited so make sure to reserve a spot soon!

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Confirmed speakers

Program

Day 1 - Tuesday, 08 September, 2015

13:00
14:15
Registration & Welcome coffee
Session 1: Cancer and Autoimmune Diseases
14:15
14:35
Welcome
14:35
15:35
Regulation of cell metabolism to support tumor growth
15:35
16:10
mTOR signaling in lymphocyte homeostasis and tumorigenesis
16:10
16:40
Coffee Break
16:40
17:15
Exploiting the Metabolic Flexibility of Th17 Cells for the Treatment of Autoimmunity and Cancer
17:15
17:35
P53 attenuates AKT signaling by modulating membrane phospholipid composition
17:35
17:55
Reprogramming GABA Metabolism towards GHB production
18:30
20:00
Reception - Belgian Beer Tasting

Day 2 - Wednesday, 09 September, 2015

Session 2: Angiogenesis and Cardiovascular Diseases
09:00
10:00
Angiogenesis revisited: endothelial metabolism as a target?
10:00
10:35
Metabolic control of lymphatic development
10:35
11:05
Coffee break
11:05
11:40
Metabolic checkpoints during vascular growth and quiescence
11:40
12:15
PGC-1 and endothelial metabolism

Zolt Arany

Perelman School of Medicine, University of Pennsylvania, US
12:15
12:35
Regulation of endothelial metabolism by laminar shear stress
12:40
13:40
Lunch
13:40
15:10
Poster session 1
Session 3: Cancer and Mitochondrial Metabolism
15:10
15:45
How mitochondrial metabolism leads to ROS production
15:45
16:20
Tricarboxylic acid cycle metabolism in cells
16:20
16:50
Coffee break
16:50
17:25
Fatty acid metabolism in cancer cells: Are we looking at the right pathway?
17:25
18:00
VEGF blockade elicits a stable metabolic shift in tumor cells
18:00
18:20
New insights into the mode of action of metformin through calcium flux modifications and its consequences on cancer cells mitochondria
19:30
22:30
Conference Dinner @ Faculty Club

Day 3 - Thursday, 10 September, 2015

Session 4: Stromal Cell Metabolism
09:00
09:35
Influence on Vessel Shape of Macrophage Metabolism in the Tumor Hypoxic Niche
09:35
10:10
Fueling T cell activation and anti-tumor immunity
10:10
10:40
Coffee break
10:40
11:15
Metabolic adaptation: implications for immunity

Russell Jones

Centre for Cancer and Cell Biology, Van Andel Research Institute, US
11:15
11:35
Role of fatty acid ß-oxidation in lymphatic development
11:35
11:55
Metabolic reprogramming of tumor-specific T cell boosts anti-tumor immunity by re-adjusting T cell metabolic fitness in the tumor microenvironment
12:00
13:00
Lunch
13:00
14:30
Poster session 2
Session 5: Metabolism in Complex Diseases
14:30
15:30
Metabolic Adaptations in Renal Cancer
15:30
16:05
Mitochondrial metabolism and the determination of cell fate
16:05
16:35
Coffee break
16:35
17:10
Obesity, Metabolism and Cancer: Mechanistic Lessons from Transdisciplinary Studies
17:10
17:45
Metabolism bottom-up: a haystack of needles
17:45
18:00
Closing remarks

Organizing committee

Abstracts

The full list of abstracts will be available on 01-09-2015 until 24-09-2015
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 01-09-2015 until 24-09-2015
This list will only be available for registered attendees of the event.