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Part of the conference series

Structural Dynamics in Cellular Communication (2nd edition)

20-21 September 2018, Brussels, Belgium
Structural Dynamics in Cellular Communication (2nd edition) - campaign visual
Structural Dynamics in Cellular Communication (2nd edition)

After a successful first edition in February 2015, with a great audience and speakers such as Nobel Prize winner Ada Yonath, we are honored to announce a second edition of this VIB Structural Biology conference.

This meeting will feature current developments in protein science with plenary sessions focusing on:

  • macromolecular machines
  • in situ structural biology
  • structural engineering & drug discovery
  • protein function/dynamics

In addition to the scientific program, conference attendees will have ample networking opportunities during breaks, reception, conference dinner and guided walk in Brussels.

Meet the Expert session with Patrick Cramer

Especially for junior researchers a ‘Meet the Expert' session with Patrick Cramer (Director at the Max Planck Institute of Biophysical Chemistry) will be organized on the 21th of September. During an informal round table discussion PhD students and postdocs will have the exclusive opportunity to ask any question/advise related to their research and careers. If you are interested in joining the session, then send an e-mail to conferences@vib.be. Seating is limited.

BECM Satellite Meeting

On September 19, the day before the Structural Dynamics in Cellular Communication meeting, there will be a BECM satellite meeting in Brussels.
If you would like to attend this satellite meeting for free please register separately. For more information see the program below.

Information for poster submissions:

The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation

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Confirmed speakers

Program

BECM Sattelite meeting - Wednesday, 19 September, 2018

This event day precedes the Structural Dynamics in Cellular Communication meeting on 20-21 September 2018 in Brussels, BE.

If you would like to attend this satellite meeting please register seperately, for free, via this link: Register for BECM Satellite Meeting

BECM Satellite Meeting

Address: Auditorium QD, building D, VUB, Pleinlaan 2, 1050, Brussels

09:30
09:45
Introduction to BECM

Rouslan Efremov

VIB-VUB Center for Structural Biology, BE
09:45
10:15
Introduction of JEOL cryoARM300 - JEOL
10:15
10:45
cryoARM300 at BECM - VIB-VUB
10:45
11:00
Coffee break
11:00
11:30
Analysis of conformational variability in cryo-EM

Pawel Penczek

The University of Texas, McGavern Medical School, US
11:30
12:00
Assembly, injection, translocation: Using cryoEM to understand the mechanism of bacterial ABC toxins

Christos Gatsogiannis

Max Planck Institute of Molecular Physiology, DE
12:00
12:30
Fibril Structure of Abeta(1-42) by Cryo-EM

Gunnar Schroeder

Computational Structural Biology, Forschungszentrum Jülich, DE
12:30
13:30
Sandwich lunch
13:30
14:00
Cryo-EM with phase plates

Radostin Danev

University of Tokyo, JP
14:00
14:30
Determining and approaching some of the physical limits in electron cryomicroscopy

Christopher Russo

LMB-MRC, UK
14:30
15:00
Microfluidic EM sample preparation for differential visual proteomics and diagnostics

Thomas Braun

Center for Cellular Imaging and Nanoanalytics (C-CINA), Biozentrum, University of Basel, CH
15:00
15:30
Coffee break
Official opening of the VIB-VUB facility for Bio Electron Cryogenic Microscopy (BECM)

Address: Auditorium QC, building Q, VUB, Pleinlaan 2, 1050, Brussels

16:00
16:05
Welcome
16:35
16:40
16:40
16:45

Caroline Pauwels

Rector VUB, BE
16:45
16:50

Philippe Muyters

Flemish Minister for Work, Economy, Innovation and Sport, BE
16:50
16:55

Hans Willems

Secretary General, FWO, BE
16:55
16:57
Acknowledgements

Rouslan Efremov

VIB-VUB Center for Structural Biology, BE
17:00
17:15
Ribbon cutting ceremony at the BECM Facility
17:15
Reception with barbecue outside the BECM Facility & VUB Restaurant

Day 1 - Thursday, 20 September, 2018

08:45
09:10
Registration & welcome coffee
09:10
09:15
Welcome by the Organizing Committee
Session 1: Macromolecular Machines
09:15
09:50
Structural hybrid methods to probe the Type III Secretion injectisome of pathogenic bacteria
09:50
10:25
Biophysics of bacteriophage tail contraction
10:25
10:55
Coffee break
10:55
11:30
Transporting cargo over long distances: insights from dynein/dynactin structures
11:30
12:05
Molecular architecture of a core bacterial cell wall synthesis complex
12:05
12:20
Cryo-EM structures of the mitochondrial calcium uniporters

Rozbeh Baradaran

MSKCC, US
Selected from abstracts
12:20
12:35
Structural insights into the human Mediator Tail module

Vincent Villeret

CNRS, FR
Selected from abstracts
12:35
13:30
Lunch
13:30
14:30
Poster session - odd numbers
Session 2: Protein Function/Dynamics
14:30
15:05
CryoEM visualization of G protein-coupled receptors
15:05
15:40
How nature harnesses entropy to tune protein function

Zachary A. Wood

Department of Biochemistry and Molecular Biology, University of Georgia, US
15:40
16:10
Coffee break
16:10
16:45
Complex Dynamics and Dynamic Complexes: NMR Studies of Large Scale Dynamics and their role in Protein Function
16:45
17:20
From Nanobodies to Megabodies for applications in cryo-EM
17:20
17:35
Conformational dynamics of a secondary multidrug transporter with single-molecule FRET

Aurélie Roth

Université libre de Bruxelles, BE
Selected from abstracts
17:35
17:50
Structural basis of quiescence and activation of the translocase motor SecA: A paradigm for the allosteric regulation of molecular motors

Srinath Krishnamurthy

Rega Institute, KU Leuven, BE
Selected from abstracts
17:50
19:00
Reception
20:00
22:30
Conference dinner

Day 2 - Friday, 21 September, 2018

08:45
09:15
Welcome coffee
Session 3: in situ Structural Biology
09:15
09:50
Integrated structural biology reveals the basis of gene transcription
09:50
10:25
Cell-cell interactions mediated by bacterial contractile injection systems

Martin Pilhofer

Department of Biology, Institute of Molecular Biology & Biophysics, ETH Zurich, CH
10:25
10:55
Coffee break
10:25
10:55
Meet the Expert session with Patrick Cramer
10:55
11:30
Imaging protein dynamics by X-ray laser
11:30
12:05
Fluorescence lifetime imaging and Förster resonant energy transfer
12:05
12:20
Cell engineering to implement live-cell structural biology: reconstruction of the exocytic machinery

Oriol Gallego

Department of Experimental and Health Sciences, University Pompeu Fabra (UPF), ES
Selected from abstracts
12:20
12:35
The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

Marisa Martin-Fernandez

Science & Technology Facilities Council, UK
Selected from abstracts
12:35
13:30
Lunch
13:30
14:30
Poster session - even numbers
Session 4: Structural Engineering & Drug Discovery
14:30
15:05
Dynamic Control of Synaptic Organizers – Shaping protein interaction networks in the synaptic cleft

Gabrielle Rudenko

Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, US
15:05
15:40
Giant protein assemblies in nature and by design
15:40
16:10
Coffee break
16:10
16:45
Structure and therapeutic targeting of bacterial S-layers
16:45
17:00
Structural activation of pro-inflammatory humancytokine IL-23 by cognate IL-23 receptor enables recruitment of the shared receptor IL-12Rb1

Yehudi Bloch

VIB-UGent Center for Inflammation Research, BE
Selected from abstracts
17:00
17:15
The structural basis of nanobody unfolding reversibility and thermoresistance

Patrick Kunz

German Cancer Research Center (DKFZ), Heidelberg, DE
Selected from abstracts
17:15
17:30
Fragment-based and Computational Methods Identify Ligandable Pockets on the von Hippel-Lindau E3 Ubiquitin Ligase

Inge Van Molle

VIB Laboratory of Structural and Molecular Microbiology, VUB, BE
Selected from abstracts
17:30
17:40
Closing remarks

Organizing committee

Jan Steyaert

VIB-VUB Center for Structural Biology, BE

Peter Tompa

VIB-VUB Center for Structural Biology, BE

Joris Messens

VIB-VUB Center for Structural Biology, BE

Savvas Savvides

VIB-UGent Center for Inflammation Research, BE

Wim Hol

Department of Biochemistry, University of Washington, BE

Abstracts

The full list of abstracts will be available on 13-09-2018 until 04-10-2018
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 13-09-2018 until 04-10-2018
This list will only be available for registered attendees of the event.