The Leuven Protein Aggregation Meeting (2nd edition)
11-13 September 2024, Leuven, Belgium
Tickets are sold out
The Leuven Protein Aggregation Meeting (2nd edition)
The Leuven Protein Aggregation Meeting (2nd edition)
Tickets are sold out
Keep me postedAdd to calendarFollowing the great success of the conference's first edition in 2022, Frederic Rousseau, Joost Schymkowitz and the Switch Lab will again bring together inspiring speakers from around the world to talk about some of the most exciting research in the protein aggregation field. With less than 150 participants in an informal setting, there will be ample opportunity for discussion and interaction among all participants. The program will include poster sessions to allow contributions from as many attendees as possible.
Come join us for this exciting meeting in Leuven’s Great Beguinage, a UNESCO world heritage site fom the 13th century. Besides the inspiring scientific program, participants will also have ample networking opportunities during the poster sessions and conference dinner.
Campaign image copyright: by Nikky Courthout , Meine Ramakers and Katerina Konstantoulea, VIB Labs
Poster information
The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation.
Host City: Leuven
Want to know more about the host city of this conference? Find out where the best restaurants, bars, or last-minute print shops are. Check the city page here.
Travel grants
We offer 5 travel grants to international junior scientists, which will reimburse travel costs up to 400 Euros.
Confirmed speakers
Program
Day 1 - Wednesday, 11 September, 2024
13:00
14:00
Registration
14:00
16:00
Session 1
14:00
14:05
Welcome
14:05
14:35
Small molecule steering of amyloid aggregation
Sheena E Radford
University of Leeds, UK
14:35
14:50
Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis
Stefano Ricagno
University of Milan, IT
Selected from abstracts
14:50
15:05
Ancestral Sequence Reconstruction of Synuclein: Insights into Evolution and Aggregation
Jean Baum
Rutgers University, US
Selected from abstracts
15:05
15:35
Tau prions in neurodegenerative tauopathies
Marc Diamond
UT Southwestern, US
15:35
16:00
Coffee break
16:00
17:45
Session 2
16:00
16:30
Understanding the life cycle of TDP-43: aggregation triggers & toxicity effectors
Magdalini Polymenidou
University of Zurich, CH
16:30
16:45
Functional Amyloid Formation is Regulated by Temperature-Sensitive Protein Domains
Timothy Audas
Simon Fraser University, CA
Selected from abstracts
16:45
17:00
Exploring the Impact of Exogenous Prion-Like Proteins on Cognitive Function
Natalia Sanchez de Groot
Universitat Autonoma de Barcelona, ES
Selected from abstracts
17:00
17:30
The thermodynamic stability of amyloid fibrils
Alexander Buell
Technical University of Denmark (DTU), DK
17:30
17:35
RNA-Driven Liquid-Liquid Phase Separation Modulates Aggregation and Cellular Interactions of PSMα3 Bacterial Amyloid
Bader Rayan
Technion-Israel Institute of Technology, IL
Poster pitch
17:35
17:40
α-Synuclein Aggregation is Triggered by Oligomeric Amyloid-β 42 via Heterogeneous Primary Nucleation
Devkee Vadukul
Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, GB
Poster pitch
17:40
17:45
A novel dimeric variant of transthyretin involved in a severe cardiomyopathy: A structural and thermodynamic characterization
Lucas Martins
Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, BR
Poster pitch
18:00
20:00
Poster session 1
With Belgian beers and tapas
20:00
Feel free to enjoy one of the many restaurants in the historic city of Leuven (not included in the registration fee)
Day 2 - Thursday, 12 September, 2024
09:00
11:00
Session 3
09:00
09:30
Molecular origami: Understanding how proteins fold and misfold in living cells
Judith Frydman
Stanford University, US
09:30
09:45
Transmissible Aβ-amyloids: implications for iatrogenic amyloidosis and the role of fibril polymorphs
Per Hammarstrom
Linkoping University, SE
Selected from abstracts
09:45
10:00
Comprehensive cryo-EM study of ex-vivo ATTR amyloidosis fibrils and its translation into detection tools.
Lorena Saelices Gomez
UT Southwestern Medical Center, US
Selected from abstracts
10:00
10:30
Thermodynamic and kinetic approaches for drug discovery to target protein misfolding and aggregation
Michele Vendruscolo
University of Cambridge, UK
10:30
11:00
Coffee break
11:00
12:10
Session 4
11:00
11:30
Mechanisms of tau assembly regulation
Lukasz Joachimiak
University of Texas Southwestern Medical Center, US
11:30
12:00
The physiological role of alpha-synuclein at the presynapse
Gabriele Kaminski Schierle
University of Cambridge, UK
12:00
12:05
How do amyloid fibrils grow? - Mechanistic insights from Φ-value analysis
Jacob Aunstrup Larsen
Technical University of Denmark, DK
Poster pitch
12:05
12:10
An in vivo model of cardiac AL amyloidosis unveils mechanisms of tissue accumulation and toxicity of amyloid fibrils
Karolina Swiderska
Team BioPIC CNRS UMR-7276 INSERM-U1262 Control of the Immune Response B and Lymphoproliferations, Limoges, FR
Poster pitch
12:10
14:15
Lunch & Poster session 2
14:30
16:30
Session 5
14:30
15:00
Finding the spark that ignites protein misfolding
Louise Serpell
University of Sussex, UK
15:00
15:15
Reversible amyloids as biomolecular memories
Thomas Michaels
ETH Zurich, CH
Selected from abstracts
15:15
15:30
Exosome, endosome and lipid modulators of Aβ aggregation and intraneuronal accumulation
Elin Esbjörner
Chalmers University of Technology, SE
Selected from abstracts
15:30
16:00
Mapping the protein-protein interactions between the proteome and aggregating proteins
Danny Hatters
University of Melbourne, AU
16:00
16:30
Coffee break
16:30
18:00
Session 6
16:30
17:00
Competition between functional amyloids: the structural basis for viral interference with the mammalian necroptosis machinery
Margie Sunde
The University of Sydney, AU
17:00
17:15
Amyloid-β curvilinear protofibrils, annular and fibril assembly and their interaction with lipid bilayers.
John Viles
Queen Mary, University of London, GB
Selected from abstracts
17:15
17:30
Exploring the relationship between aortic amyloid and other risk factors associated with aortic pathologies
Jillian Madine
Institute of Systems, Molecular and Integrative Biology, University of Liverpool, GB
Selected from abstracts
17:30
18:00
Amyloid fibril structures from systemic amyloidosis
Marcus Fändrich
Institute of Protein Biochemistry, Ulm University, DE
18:00
18:30
Systemic amyloidoses – research gaps and clinical needs
Stefan Schönland
Heidelberg University Hospital, University of Heidelberg, De
Selected from abstracts
18:30
21:30
Conference dinner
Additional fee
Day 3 - Friday, 13 September, 2024
09:00
11:00
Session 7
09:00
09:30
Quantifying Pathology of Dementias with Proteomics
Judith Steen
Harvard Medical School & Boston Children's Hospital, US
09:30
09:45
Updating The Research Community on the progress of The AD/ADRD Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs
Rakez Kayed
University of Texas Medical Branch, US
Selected from abstracts
09:45
10:00
High-resolution neutron spectroscopy as a tool to study protein aggregation in liquid solution
Tilo Seydel
Institut Max von Laue - Paul Langevin, FR
Selected from abstracts
10:00
10:30
Uncovering neurotoxic mechanisms of self-propagating huntingtin aggregates in Drosophila
Erich Wanker
Max Delbrück Center for Molecular Medicine, Berlin, DE
10:30
11:00
Coffee break
11:00
12:30
Session 8
11:00
11:30
The BRICHOS domain of Bri2 inhibits IAPP amyloid formation in islet-like stem cell clusters
Gunilla T Westermark
Uppsala University, SE
11:30
11:45
Predicting protein-RNA interactions relevant for phase separation and transition
Selected from abstracts
11:45
12:00
The role of (sphingo-)lipid homeostasis in endo-lysosomal integrity and Tau spreading
Carmen Nussbaum-Krammer
Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, Ludwig Maximilians University of Munich, DE
Selected from abstracts
12:00
12:30
Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids
Sjors Scheres
MRC Laboratory of Molecular Biology, Cambridge, UK
12:30
14:00
Poster prizes, Closing remarks & Lunch
14:00
End of the conference
Organizing committee
Frederic Rousseau
Switch Laboratory, VIB-KU Leuven Center For Neuroscience, BE
Joost Schymkowitz
Switch Laboratory, VIB-KU Leuven Center For Neuroscience, BE
Hannah Wilkinson
Switch Laboratory, VIB-KU Leuven Center For Neuroscience, BE
Filip Claes
Switch Laboratory, VIB-KU Leuven Center For Neuroscience, BE
Abstracts
We are delighted that the International Society of Amyloidosis will offer four awards, each of 1150 euros, for the best abstracts as rated by the Organizing Committee! These awards are for early career scientists (PhD students and postdocs) and can be used to cover the cost of attending ProAgg24 (reimbursing travel, accomodation & registration). Announcements will be made during the week of June 10th!
The full list of abstracts will be available on 28-08-2024 until 13-12-2024
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Attendees
The full list of attendees will be available on 28-08-2024 until 13-12-2024
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Sponsors
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Platinum
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