The 5th International TRP meeting
17-19 September 2025 - Leuven
Supported by VIB Training & Conferences
The 5th International TRP meeting
The 5th International TRP meeting
Supported by VIB Training & Conferences
Keep me postedAdd to calendarTRP2025 is the 5th edition of an international meeting that brings together researchers interested in Transient Receptor Potential (TRP) ion channels. The meeting covers key aspects of TRP channel research, from structural and molecular analyses of TRP channel function, to their roles in health and disease, and the development of TRP channel-based therapies. These topics will be discussed during invited lectures by renowned experts in the field, poster sessions and short talks from selected abstracts. In the informal setting of Leuven’s Great Beguinage, a UNESCO World Heritage site from the 13th century. The meeting offers ample opportunity for discussion and interaction among all participants - junior and senior researchers from academia and industry.
Confirmed speakers
Alex Binshtok
Alex Binshtok
Faculty of Medicine and The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, IL
Ingrid Carvacho
Ingrid Carvacho
Department of Translational Medicine, Faculty of Medicine, Universidad Católica del Maule, Talca, CL
Sven-Eric Jordt
Sven-Eric Jordt
Duke University, School of Medicine, Department of Anesthesiology, US
Gabriela Krasteva-Christ
Gabriela Krasteva-Christ
Institute for Anatomy and Cell Biology, Saarland University, DE; PharmaScienceHub (PSH), DE; Center for Gender-specific Biology and Medicine (CGBM), DE
Andrea Lunardi
Andrea Lunardi
Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, IT
Víctor Meseguer Vigueras
Víctor Meseguer Vigueras
Instituto de Neurociencias, Universidad Miguel Hernández-CSIC, ES
Arn van den Maagdenberg
Arn van den Maagdenberg
Departments of Human Genetics and Neurology, Leiden University Medical Center, NL
Arthur Neuberger
Arthur Neuberger
Walther Straub Institute of Pharmacology & Toxicology, Faculty of Medicine, LMU Munich, DE
Program
Day 1 - Wednesday, 17 September, 2025
18:00
19:00
Registration
19:00
20:00
Opening keynote lecture
chair: Karel Talavera
19:00
20:00
TRP channels and control of the most dangerous animal in the world
Craig Montell
University of California, Santa Barbara, US
Keynote speaker
Bernd Nilius – Honorary guest
20:30
22:30
Get-together reception & poster session
Day 2 - Thursday, 18 September, 2025
08:45
09:00
Welcome word
by Thomas Voets
09:00
11:00
Structure-function of TRP channels 1
chair: Tibor Rohacs
09:00
09:25
A cool tale of a warm channel
Juan Du
Northwestern University, US
09:25
09:50
It’s complicated: mapping the calcium regulation mechanism of a critical pain receptor
Candice Paulsen
Yale University, US
09:50
10:00
Structural mechanisms of TRPM3 inactivation and regulation by calmodulin
K V Nageswar
Indian Institute of Technology Kanpur, IN
Selected from abstracts
10:00
10:25
TRPC3 at the Center: PIP2 Regulation, SK3 Modulation, and ASD Susceptibility
Oleksandra Tiapko
Medical Physics and Biophysics, Medical University of Graz, AT
10:25
10:45
Coffee break
10:45
12:00
Structure-function of TRP channels 2
chair: Vladimir Chubanov
10:45
11:10
TRP Channels on a leash – functional regulation through intrinsically disordered regions
Ute Hellmich
Friedrich Schiller University Jena, DE
11:10
11:35
Structural pharmacology of TRPV6
Arthur Neuberger
Walther Straub Institute of Pharmacology & Toxicology, Faculty of Medicine, LMU Munich, DE
11:35
11:45
Distinct subcellular mechanisms enable lysophosphatidylcholine and arachidonic acid to amplify function of TRPV2
Marvin Meyer
Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, DE
Selected from abstracts
11:45
12:00
Posterblitz odd
12:00
12:45
Lunch
12:45
14:45
Poster session
15:00
16:45
Sensational TRP channels 1
Chair: Joris Vriens
15:00
15:25
Modulation of epidermal TRPV1 for attenuating peripheral neuropathies
Antonio Ferrer-Montiel
IDiBE, Universitas Miguel Hernández, ES
15:25
15:50
T(r)IPPING THE SCALES: mimicking cold pharmacologically
Mahendra Bishnoi
BRIC-National Agri-Food and Biomanufacturing Institute, IN
15:50
16:00
Molecular and functional modulation of candidate thermosensitive TRPA channels by natural repellent ligands in haematophagous insects
Pelin Kaya
GIGA Institute, Molecular Biology of Sensory Systems, University of Liège, BE
Selected from abstracts
16:00
16:25
In vivo optical recording of the TRP channel activity at the corneal nerve terminal
Víctor Meseguer Vigueras
Instituto de Neurociencias, Universidad Miguel Hernández-CSIC, ES
16:25
16:45
Coffee break
16:45
17:55
Sensational TRP channels 2
Chair: Philippe Gailly
16:45
17:10
Biophysical and structural plasticity of nociceptive free nerve endings underlying pathological pain
Alex Binshtok
Faculty of Medicine and The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, IL
17:10
17:20
TRPV1-TRPV2 interactions. Less than the sum of their parts
George Oprita
Department of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, RO; National Center for Brain Research, Research Institute for Artificial Intelligence, Romanian Academy, Bucharest, RO
Selected from abstracts
17:20
17:30
Activity-dependent agonist action of acrolein on TRPV1
Enrique Velasco
Laboratory of Ion Channel Research, Dept. of Cellular and Molecular Medicine, KU Leuven, BE; VIB Center for Brain & Disease Research, BE
Selected from abstracts
17:30
17:55
Beyond Taste: TRPM5 and tracheal tuft cells in airway protection
Gabriela Krasteva-Christ
Institute for Anatomy and Cell Biology, Saarland University, DE; PharmaScienceHub (PSH), DE; Center for Gender-specific Biology and Medicine (CGBM), DE
18:30
23:00
Conference dinner & poster session
Included in the registration ticket.
Day 3 - Friday, 19 September, 2025
09:00
11:00
TRP channels and genetic diseases
Chair: Rudi Vennekens
09:00
09:25
Gain of function mutations provide novel insights into polycystin physiology
Markus Delling
UC San Francisco, US
09:25
09:50
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice
Jeremy Sullivan
Johns Hopkins University School of Medicine, US
09:50
10:00
Selectivity of ionic pathways through TRPM3 channel variants and mutants
Júlia Castro-Marsal
Institute of Physiology and Pathophysiology, Philipps-Universität Marburg, DE
Selected from abstracts
10:00
10:25
TRP channel mutations as key factors for chronic pain susceptibility
Roberta Gualdani
University of Louvain, BE
10:25
10:45
Coffee break
11:00
12:15
TRP channel translational research 1
Chair: Djalila Mekahli
10:45
11:10
TRP channels as targets of tobacco product additives: Behavior, toxicology and insights from regulatory science
Sven-Eric Jordt
Duke University, School of Medicine, Department of Anesthesiology, US
11:10
11:35
Mouse models of migraine and their use to understand disease and treatment targets
Arn van den Maagdenberg
Departments of Human Genetics and Neurology, Leiden University Medical Center, NL
11:35
11:45
Role of TRPV3 in colitis-associated cancer
Maria Miraglia
Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, IT
Selected from abstracts
11:45
12:00
Posterblitz even
12:00
12:45
Lunch
12:45
14:45
Poster session
15:00
16:30
TRP channel translational research 2
Chair: Marc Freichel
15:00
15:25
TRP channels function during oocyte maturation and egg activation
Ingrid Carvacho
Department of Translational Medicine, Faculty of Medicine, Universidad Católica del Maule, Talca, CL
15:25
15:50
TRP channels in bladder pathophysiology: From sensing to symptoms
Wouter Everaerts
Department of Cellular and Molecular Medicine, KU-Leuven, BE
15:50
16:00
TRPV4 channels mediate pulmonary surfactant protein A and D secretion as well as basal cell differentiation to ciliated cells
Philipp Alt
Walther-Straub-Institute of Pharmacology and Toxicology, LMU-Munich. Germany, DE
Selected from abstracts
16:00
16:25
TRPM8 and Prostate Cancer: friends or foes?
Andrea Lunardi
Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, IT
16:25
16:45
Coffee break
16:45
17:55
TRP channel drug development
Chair: Thomas Voets
16:45
17:10
Targeting TRPM channels to treat neglected tropical disease
Jonathan Marchant
Medical College of Wisconsin, US
17:10
17:20
RAGE and TRPV1 mediate acid hypersensitivity in human skin inflammation
Felix Resch
Institute of Physiology, Center for Physiology and Pharmacology, AT
Selected from abstracts
17:20
17:30
TRPM3 Modulates Seizure Susceptibility Across Multiple Acute Seizure Models: Implications for Novel Anti-seizure Medications
Ilhem Dallali
Laboratory of Ion Channel Research, VIB-KU Leuven Center for Brain & Disease Research, BE; Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, University of Leuven, BE
Selected from abstracts
17:30
17:55
Effects of TRPC channel inhibition
Andreas Wunder
Freelance consultant, DE
17:55
18:15
Concluding remarks – end of meeting
by Thomas Voets
Organizing committee
Thomas Voets
VIB-KU Leuven Center for Brain & Disease Research, BE; CMM-KU Leuven, BE
Rudi Vennekens
Department of Cellular and Molecular Medicine, KU-Leuven, BE
Karel Talavera Pérez
Department of Cellular and Molecular Medicine, KU-Leuven, BE
Wouter Everaerts
Department of Cellular and Molecular Medicine, KU-Leuven, BE
Djalila Mekahli
Department of Cellular and Molecular Medicine, KU-Leuven, BE
Joris Vriens
Department of Development and Regeneration, KU-Leuven, be
Janine Brunner
VIB-VUB Center for Structural Biology, BE
Marc Freichel
Institute of Pharmacology, DE
Roberta Gualdani
University of Louvain, BE
Philippe Gailly
Université catholique de Louvain, Institute of Neuroscience, BE
Andrei Segal
VIB-KU Leuven Center for Brain & Disease Research, BE; CMM-KU Leuven, BE
Annelies Janssens
VIB-KU Leuven Center for Brain & Disease Research, BE; CMM-KU Leuven, BE
Andrea Soto Véres
VIB-KU Leuven Center for Brain & Disease Research, BE; CMM-KU Leuven, BE
Abstracts
Poster information
The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation.
The full list of abstracts will be available on 01-09-2025 until 19-12-2025
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Attendees
The full list of attendees will be available on 01-09-2025 until 19-12-2025
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Sponsors
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Silver
Silver
Silver
Bronze
