Claudia Ctortecka

As Group Leader of the Single Cell Unit at Amsterdam UMC and Vrije Universiteit Amsterdam, I establish and direct a research program at the intersection of single-cell and spatial proteomics, neurobiology, and oncology, within the ADORE program.

Previously, as a CLP Translational Proteomics Fellow at Northwestern University, I worked with Neil Kelleher's team to develop top-down proteomics approaches complementing single-cell bottom-up workflows, with an emphasis on kidney tissue heterogeneity and brain tumor progression. Before that, I was a postdoctoral researcher in Steve Carr's lab at the Broad Institute of MIT and Harvard, where I advanced single-cell proteomics and immunopeptidomics workflows using the timsTOF platforms. My Ph.D. at the Vienna BioCenter, under Karl Mechtler and Sasha Mendjan, centered on the development of the first commercially available single-cell proteomics approach with the proteoCHIP and profiling of cardiac organoids.

As Chair of the Single Cell Initiative at the Human Proteome Organization, I advocate for reproducibility and collaboration across the proteomics community.