Dr. Pearce obtained her B.A. from Cornell University in 1998 and her Ph.D. in 2005 at the University of Pennsylvania in Philadelphia, where she studied the regulation of T cell responses during infection. During her postdoctoral studies, also at the University of Pennsylvania, she began her research into how cellular metabolic processes govern immune responses to infection and cancer. In 2009, Dr. Pearce launched her independent research career at the Trudeau Institute in Saranac Lake, New York. In 2011, she moved to the Department of Pathology and Immunology at Washington University School of Medicine in St. Louis where she continued investigating the connection between metabolism and immune cell function. In 2015, Dr. Pearce moved her research group to Europe to become a Director at the Max Planck Institute for Immunobiology and Epigenetics in Freiburg, Germany. In 2018 she was awarded the Leibniz Prize for her work on immune cell metabolism. Her research continues to investigate metabolic pathways in immune cells, with a view to targeting these pathways for therapy.