Henk is full professor at the Science and Medical faculty and head of the Department of Molecular Biology and Director of the Radboud Institute for Molecular Life Sciences of the Science faculty at Radboud University, Nijmegen.
His research aims at unravelling the molecular basis of development and differentiation emanating from the genome and epigenome in the context of health and disease with emphasis on cancer. To this end, state-of-the-art technological developments are applied ranging from single molecule studies through to genome wide elucidation of genetic and epigenetic pathways and mechanisms.
Henk was the coordinator of EU FP7 High Impact Project BLUEPRINT that focuses on distinct types of haematopoietic cells from healthy individuals and on their malignant leukaemic counterparts. It aims at generating reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease.
He is member of EMBO since 1992, was the chair of Scientific Steering Committee of the International Human Epigenome Consortium (IHEC) from 2012-2016, he is member of the Council off Scientists of Human Frontier Science Program Organization (HFSPO), Program Committee member for the International Cancer Genome Consortium (ICGC).
Current research focuses on the role of epigenetics in embryonic stem cells and in Innate Immune Memory.