László Csanády

My lab studies the structure and function of ion channels: transmembrane protein pores that allow passage of some type of ion across a biological membrane. Our experimental approaches include recording and analysis of single-channel and macroscopic patch-clamp currents, site-directed mutagenesis, protein biochemistry, and mathematical modeling. Our studies are focused on two target proteins, the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel and the transient receptor potential melastatin 2 (TRPM2) cation channel.