Shinya Kuroda

Shinya Kuroda is the professor at Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan since 2006.

He started his career as a biochemist when he was a graduate student since 1991. He studies the mechanism of signal transduction of small GTPases, the Ras family. After the graduation, he became an assistant professor and studied the mechanism of signal transduction of small GTPases, Cdc42 and Rac. He had an opportunity to join the neural computation lab at ATR (Prof. Mitsuo Kawato), and started computational biology of signal transduction. He became independent as a associate professor at Department of Computer Science, University of Tokyo in 2002, and started systems biology study of signal transduction by integrating “dry” computer simulation and “wet” experimental biology. In particular, he investigated systems biology of ERK-signaling networks that regulate cell fate-determination (cell growth, differentiation and death). He realized the temporal patterns of growth factors as well as of ERK determines the cell-fate, and picked up insulin as a next target because in vivo temporal patterns of insulin are well-investigated and closely related to pathogenesis of type 2 diabetes. He became a full professor at the current position in 2006, and started systems biology of insulin signaling. Recently, we studied the trans-omic analysis of insulin action by integrating multi-omic data. For detail, visit our website (www.kurodalab.org).