Vera Moiseenkova-Bell
Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, US
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Biography
We are interested in understanding structure and function of Transient Receptor Potential (TRP) channels which have been implicated in a diverse range of cellular processes, including pain sensation, neuronal development, cardiovascular and renal pathophysiology, and cancer. Currently, the Moiseenkova-Bell laboratory has two main areas of research: First is to determine the structural basis of TRP channel activation, inhibition and desensitization mechanisms by utilizing cryo electron microscopy (cryo-EM). Second is to understand how TRP channels regulate cellular functions and the role of their dysregulation in human disease.