Below you can find the presenters per session for Thursday and Friday.
Thursday 16-9 | 14:00-15:00
Session 1 TRP Channels in health and disease I– Moderator Rudi Vennekens
- Characterization of calcium-coupled GPCRs to modulate cystogenesis in autosomal dominant polycystic kidney disease (ADPKD)
- Dorien Van Giel, LICR VIB-KULeuven BE
- How does TRPC6 gets into red blood cells?
- Lars Kaestner, Saarland University, DE
- Osmoregulatory role of TRPV4 in human podocytes
- Martin Hanyicska, University of Debrecen, HU
- Interdependent regulation of polycystins influences starvation-induced autophagy and cell dead
- Jean Paul Decuypere, KU Leuven, BE
- The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus
- Markus Delling, UCSF, US
Session 2. Pharmacology of TRP channels I – Moderator Wouter Everaerts
- Rapamycin activates TRPM8 via novel mechanisms
- Balázs István Tóth, University of Debrecen, HU
- Inhibition of TRPM8 by Phenazopyridine
- Noémie Luyts, LICR VIB-KU Leuven BE
- Structural mechanism of TRPV3 channel inhibition by the natural, plant-derived coumarin osthole
- Arthur Neuberger, Columbia University, US
- TRPM5 activity in the pancreatic beta cell is potentiated with glimepiride and stimulates glucose-induced insulin secretion
- Koenraad Philippaert, LICR VIB-KULeuven BE
- Pharmacology of Transient Receptor Potential cation (TRP) channels using different activation stimuli
- Alison Obergrussberger, Nanion Technologies , DE
Session 3. Cellular regulation of TRP channel function – Moderator Karel Talavera
- A duo of redox-sensitive cysteines controls TRPM3 activity
- Katharina Held, LICR VIB-KULeuven BE
- Evidence of PIP2 interaction with TRPC3 as a determinant of current rectification
- Oleksandra Tiapko, Medical University of Graz, AT
- Regulation of TRPM8 function by constitutive phosphorylation
- María Pertusa, Universidad de Santiago de Chile, CL
- TRPC4 and GIRK encode neuronal responses to coincident Gi/o-Gq/11 signals of variable strengths
- Michael X.Zhu, The University of Texas Health Science Center at Houston, US
- Dual Effects of Phosphatidylinositol on TRPV1 regulation Involve Functionally Distinct Binding Sites
- Aysenur Yazici, Rutgers, New Jersey Medical School, US
Session 4. TRP channels and Pain I – Moderator Joris Vriens
- TRP-related experimental human pain models
- Stefan Heber, Medical University of Vienna, AT (ingediend door Michel Fisher)
- TRP functionality in patients suffering from paclitaxel-induced peripheral neuropathy: Interim data
- Heleen Marynissen, University Hospitals Leuven, BE
- Combining topical agonists with the recording of event-related brain potentials to probe the functional involvement of TRPM8, TRPA1 and TRPV1 in heat and cold transduction in the human skin
- Arthur Courtin, UCLouvain, BE
- TRPA1 contributes to lengthening contraction-induced muscular mechanical hyperalgesia
- Hiroki Ota, Niigata Univ. Health Wel., Niigata, JP; Nagoya Univ., Nagoya, JP
- TRPM3 – novel target to alleviate chemotherapy-induced peripheral neuropathic pain (CIPNP)
- Vincenzo Davide Aloi, LICR VIB-KULeuven BE
Session 5. New approaches in TRP channel research Moderator Thomas Voets
- Using a GCaMP3 mouse model to investigate functional expression of transient receptor potential (TRP) channels in endometriosis
- Eleonora Persoons, LICR VIB-KULeuven BE
- Transient receptor potential melastatin 4 (TRPM4) contributes to hilar mossy cell loss during temporal lobe epilepsy
- Miklós Kecskés, University of Pécs, HU
- An integrated approach to monitor TRP channel activity during pain development
- Marie Mulier, LICR VIB-KULeuven BE
- The effect of TRPM4 ion channels on glycaemic control during pregnancy.
- Caroline Wuyts, LICR VIB-KULeuven BE
Session 6. TRP channels in development and differentiation -Moderator Geert Bultynck
- TRP channel expression correlates with the epithelial-mesenchymal transition and high-risk endometrial carcinoma.
- Charlotte Van den Eynde, LICR VIB-KULeuven BE
- P53 represses TRPM4 expression in HCT 116 colorectal cancer cell line
- Sven Kappel, University of Bern, CH
- Inhibitory function of TRPA1 channels in TGF-β1-driven fibroblast to myofibroblast differentiation
- Alexander Dietrich, LMU-Munich, DE
- TRPV2 is indispensable for normal placental development and fetal growth.
- Katrien De Clercq, LICR VIB-KULeuven BE
- Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos
- Marc Freichel, Heidelberg University, DE
Friday 17-9 | 14:00-15:00
Session 1. TRP channels in the heart – Moderator Rudi Vennekens
- TRPM4 in radiation-induced cardiac remodeling.
- Harlyne Mpweme, Normandie Université, FR
- No functional TRPA1 in cardiomyocytes
- Natalia S. Rojas-Galvan, Medical University of Vienna, AT
- Genetic background influences expression and function of the cation channel TRPM4 in the mouse heart
- Rebekka Medert, Heidelberg University, DE
- TRPM4 as new target in cardiac arrhythmias
- Frone Vandewiele, LICR VIB-KULeuven BE
Session 2. TRP channels and Pain II – Moderator Wouter Everaerts
- 20 years of TRPV4 - recent findings re TRPV4's role in neural injury
- Wolfgang Liedtke, Duke University, US;
- Modulation of the chemosensory cation channel TRPA1 by cholesterol reducing drugs
- Justyna Startek, LICR VIB-KULeuven BE
- Involvement of transient receptor potential vanilloid 2（TRPV2）in mechanical nociception of adult mice
- Kimiaki Katanosaka, Chubu Univ., Kasugai, JP
- Unraveling the molecular characterization of the still neglected satellite glial cells
- Ana Peigneur, LICR VIB-KULeuven BE
- Investigation of thermosensitive Transient Receptor Potential (TRP) ion channels in the human dental pulp
- Árpád Kunka, University of Debrecen, HU
Session 3. Pharmacology of TRP channels II -Moderator Karel Talavera
- Modality-specificity of TRPV1 antagonists as the key to understanding their adverse effects
- Jan Daniluk, LICR VIB-KULeuven BE
- Structure and ligand modulation of an ancient TRP channel from Saccharomyces cerevisiae
- Tofayel Ahmed, University of Pennsylvania, US
- TRPA1 Ion Channel Modulation By Sigma-1 Receptor
- Jorge Fernández-TrillInstituto de Neurociencias de Alicante. UMH-CSIC, ES
- Optical Lipid Clamp Analysis And Md Simulations Suggest Lipid Binding Domain 2 (L2) As The Primary Site For Trpc3 Regulation By DiacylglycerolsS
- Hazel Erkan, Medical University of Graz, AT
Session 4. TRP channels and human genetics – Moderator Joris Vriens
- Functional characterization of de novo mutations in human TRPM3 related to developmental and epileptic encephalopathies
- Evelien Van Hoeymissen, LICR VIB-KULeuven BE
- Identification and Functional Characterization of a novel TRPM7 mutation associated with trigeminal neuralgia
- Roberta Gualdani, UCLouvain, BE - Yale School of Medicine, US
- Functional Characterization of a PCCD-Associated Mutation in TRPM4
- Andy Pironet, LICR VIB-KULeuven BE
- Human TRPA1 Single Nucleotide Polymorphisms
- Cosmin Ciotu, Medical University of Vienna, AT
- Disease-related TRPM3 mutations in human render the channel overactive via different
- Siyuan Zha, Rutgers, New Jersey Medical School, US
Session 5. TRP channels and temperature sensing – Moderator Thomas
- The role of TRPV1 and TRPM2 in warm temperature detection
- Muad Abd El Hay, Heidelberg University, DE
- TRPM2 and temperature detection in the hypothalamus
- Gretel Kamm, Heidelberg University, DE
- Basic characteristics of TRPC5 as a cold-activated channel
- Alexandra Ptakova, Charles University, Prague, CZ
- The molecular nature of temperature dependence of the TRPM2 channel
- Adam Bartok, Semmelweis University, HU
- Role of the extracellular cap domain in the TRPV1 gating mechanism
- Kirill D. Nadezhdin, Columbia University, US
Session 6. TRP Channels in health and disease II– Moderator Katrien De Clercq
- Oestradiol Triggers Airway Sensory Nerve Activation via a TRPM3-P2X2/3 Ion Channel Axis
- Sara Bonvini, AstraZeneca, SE; Imperial College, GB
- Glycaemic effects and plasma exposure of steviol glycosides and their metabolites in mice and men with type 2 diabetes
- Caroline Simoens, LICR VIB-KULeuven BE
- Photopharmacological sculpturing of TRPC-mediated Ca2+ signals in mast cells enables NFAT activation without concomitant degranulation
- Denis Krivić, Medical University of Graz, AT
- TRPV3 expression in normal human epidermal keratinocytes is enhanced by TLR3 activator polyinosinic-polycytidylic acid (poly(I:C))
- Anita Vladár, University of Debrecen, HU
- The role of TRPV4 in a house dust mite - induced asthma model
- Robbe Naert, LICR VIB-KULeuven BE