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The Leuven Protein Aggregation Meeting (3rd edition)

9-11 September 2026, Leuven, Belgium
Supported by VIB Training & Conferences
Registration by invitation only.
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The Leuven Protein Aggregation Meeting (3rd edition)

The Leuven Protein Aggregation Meeting (3rd edition)

Registration by invitation only. The selection deadline was 25 May. Submissions are now closed.

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We are delighted to announce the third edition of The Leuven Protein Aggregation meeting, from 9th to 11th September 2026.

Once again, we will bring together leading scientists and inspiring speakers from around the world to share the latest breakthroughs in protein aggregation.

With 150 participants in an informal, interactive setting, the meeting offers a great opportunity for in-depth discussions and networking. The program will feature stimulating talks and poster sessions, ensuring that as many attendees as possible can contribute to the scientific exchange.

The meeting takes place again in the beautiful Great Beguinage of Leuven, a UNESCO World Heritage site dating back to the 13th century. In addition to the cutting-edge scientific program, participants will enjoy ample networking opportunities during poster sessions and the conference dinner.

New this year: Participants will be invited to register only after their abstracts have been reviewed, ensuring that those selected can attend. The abstract submission deadline was 25 May 2026. The review is currently ongoing.

We look forward to welcoming you to Leuven for another stimulating and inspiring meeting!

Campaign image copyright: Sandrine Da Cruz, VIB Center for Neuroscience Leuven

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Confirmed speakers

Meytal Landau
Meytal Landau - VIB Training & Conferences - Speaker picture
Meytal Landau

Meytal Landau

CSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron (DESY), and Universitätsklinikum Hamburg-Eppendorf (UKE), DE; Technion – Israel Institute of Technology, IL

Program

Day 1 - Wednesday, 09 September, 2026

13:00
14:00
Registration and welcome coffee
14:00
14:10
Welcome word
14:10
15:40
Session 1
14:10
14:40
Amyloid Polymorphism: More than the Fibril Core
14:40
14:55
A chaperone/proteasome-based fragmentation machinery essential for aggrephagy

Mario Mauthe

University medical center Groningen (UMCG), NL
Selected from abstracts
14:55
15:10
Extracellular Vesicles From Parkinson’s Disease Stool Samples Exhibit Seed Amplification Activity

Livia Civitelli

University of Oxford, GB
Selected from abstracts
15:10
15:40
Tau condensation and aggregation
15:40
16:10
Coffee break
16:10
17:30
Session 2
16:10
16:25
Formation of GVBs: a protective neuron-specific response to protein aggregation

Wiep Scheper

Amsterdam UMC - Vriije Universiteit, NL
Selected from abstracts
16:25
16:40
Amyloid Folds as Compatibility Landscapes: From Polymorphism to Programmable Assemblies

Nikolaos Louros

UT Southwestern Medical Center, US
Selected from abstracts
16:40
17:10
Virulent and antimicrobial amyloids: structural plasticity and RNA regulation

Meytal Landau

CSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron (DESY), and Universitätsklinikum Hamburg-Eppendorf (UKE), DE; Technion – Israel Institute of Technology, IL
17:10
17:15

Hasse Hedeby

Fidabio
Sponsored talk
17:15
17:20

Michael Thomas

Sysmex
Sponsored talk
17:20
17:25

Stefan Pellenz

Hologic Diagenode
Sponsored talk
17:25
17:30

Tobias Pusterla

BMG Labtech
Sponsored talk
17:30
19:30
Poster session 1 & reception with Belgian beers

Feel free to enjoy one of the many restaurants in the historic city of Leuven (not included in the registration fee)

Day 2 - Thursday, 10 September, 2026

08:30
09:00
Welcome coffee
09:00
10:30
Session 3
09:00
09:30
Bringing structure to pathological protein assembly in motor neuron diseases and associated dementias
09:30
09:45
FibrilPaints: from amyloid binders to diagnostic tools

Françoise Dekker

Utrecht University, NL
Selected from abstracts
09:45
10:00
RNA interactions drive structural and functional diversification of α-synuclein fibrils

Gian Tartaglia

Italian Institute of Technology (IIT), IT
Selected from abstracts
10:00
10:30
Proteostasis dysfunction in aging and neurodegenerative disease
10:30
11:00
Coffee break
11:00
12:30
Session 4
11:00
11:30
Prion strain conformations and their phenotypic consequences
11:30
11:45
The cellular phase of Alzheimer’s disease

Bart De Strooper

VIB-KU Leuven Center For Neuroscience, BE & UK Dementia Research Institute, UK
11:45
12:00
Sequence determinants of selective co-assembly in RHIM amyloids

Miguel Mompeán

Blas Cabrera Institute of Physical Chemistry, ES
Selected from abstracts
12:00
12:30
Mapping the Structural Landscape and Interactome of Amyloids
12:30
13:00
Lunch
13:00
15:00
Poster session 2
15:15
16:30
Session 5
15:15
15:45
Decoding compartment-specific mechanisms of TDP 43 and FUS proteinopathies
15:45
16:00
Mitochondrial protection against proteotoxicity of aggregate accumulation

Wolfgang Voos

Institute of Biochemistry and Molecular Biology, University of Bonn, DE
Selected from abstracts
16:00
16:15
The roles of microenvironment and of an overloaded secretory pathway on amyloid aggregation: updates from ex vivo Cryo EM

Stefano Ricagno

University of Milan, IT
Selected from abstracts
16:15
16:30
Site-specific phosphorylation of Ser352 drives aggregation of Tau R4 under acidosis conditions

Assaf Friedler

the Hebrew University of Jerusalem, IL
Selected from abstracts
16:30
17:00
Coffee break
17:00
18:15
Session 6
17:00
17:30
Visualizing mitochondrial proteostasis under stress

Kenneth Ehses

Institute of Neuropathology, University Medical Center Göttingen, DE
17:30
17:45
Insoluble tau seeds found in cognitively normal cases differ by density from those occurring in Alzheimer's Disease

Diana Acosta Ingram

Department of Pathology, Case Western Reserve University School of Medicine, Cleveland OH, 44106, US
Selected from abstracts
17:45
18:00
3D atomic structure reveals evolution of prions in templated amplification in vitro

Jan Bieschke

UCL, GB
Selected from abstracts
18:00
18:15
Secondary nucleation of α-Synuclein drives Parkinson’s disease pathology

Suman De

University of Sheffield, GB
Selected from abstracts
18:30
22:00
Reception and conference dinner

additional fee

Day 3 - Friday, 11 September, 2026

08:30
09:00
Welcome coffee
09:00
10:30
Session 7
09:00
09:30
Molecular determinants and protective mechanisms against TDP-43 pathology
09:30
09:45
Molecular structure and self-assembly in functional bacterial amyloid

Daniel Otzen

iNANO and Department of Molecular Biology and Genetics, Aarhus University, DK
Selected from abstracts
09:45
10:00
Allosteric amyloid catalysis by coiled coil fibrils

Sisira Mambram Kunnath

Ilse Katz Institute (IKI) for Nanoscale Science and Technology, Ben-Gurion University of the Negev, Beer Sheva, Israel. , IL; Department of Chemistry, Ben-Gurion University of the Negev, Beer Sheva, Israel, IL
Selected from abstracts
10:00
10:30
Mechanistic and thermodynamic studies of alpha-synuclein lipid-binding and aggregation through systematic lysine to glutamine mutagenesis
10:30
11:00
Coffee break
11:00
12:30
Session 8
11:00
11:30
Tau as a Molecular Clock of Brain Aging: PTM Stoichiometry Encodes Biological Age and Disease State

Judith Steen

Harvard Medical School & Boston Children's Hospital, US
11:30
11:45
Murine Brain Amyloid Fibrils and Lipid-Associated Fibrils

Gunnar Schroeder

Computational Structural Biology, Forschungszentrum Jülich, DE
Selected from abstracts
11:45
12:00
Dynamics of the α-Synuclein fuzzy coat regulate fibril core accessibility and aggregation mechanisms

Jean Baum

Rutgers University, US
Selected from abstracts
12:00
12:30
Iatrogenic Alzheimer’s disease and its implications
12:30
13:00
Closing words and poster prize ceremony
13:00
14:00
Lunch

Organizing committee

Abstracts

The full list of abstracts will be available on 26-08-2026 until 11-12-2026
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 26-08-2026 until 11-12-2026
This list will only be available for registered attendees of the event.