Ralph DeBerardinis

Ralph DeBerardinis, M.D., Ph.D. is a pediatrician, biochemical geneticist and physician-scientist. He is an Investigator in the Howard Hughes Medical Institute, Director of the Eugene McDermott Center for Human Growth and Development at the University of Texas Southwestern Medical Center, and Director of the Genetic and Metabolic Disease Program in UT Southwestern’s Children’s Research Institute. Dr. DeBerardinis received a B.S. in Biology from St. Joseph’s University, M.D. and Ph.D. degrees from the University of Pennsylvania and clinical training at Children’s Hospital of Philadelphia. The DeBerardinis lab studies the role of altered metabolic pathways in human diseases, particularly cancer and inborn errors of metabolism. The lab uses metabolomics and isotope tracing to characterize disease-associated metabolic states in patients, and model systems to explore how metabolic perturbations contribute to tissue dysfunction. Dr. DeBerardinis has been elected to the National Academy of Sciences, National Academy of Medicine and Association of American Physicians.