Tom Cupedo

Tom Cupedo is an associate professor of Hematology at the Erasmus MC Cancer Institute in Rotterdam the Netherlands. Trained as an immunologist, Tom’s research has always revolved around stromal cell – immune cell interactions, and his lab has studied these in a wide array of settings including lymph node development and tissue repair. In recent years, the lab has been exclusively focused on stromal –immune interactions in the bone marrow of patients with multiple myeloma, a cancer of malignant plasma cells and the second most prevalent blood cancer in adults. Tom’s team identified a myeloma-supportive bone marrow stromal cell niche, and charted the stromal and immune transcriptional landscape of newly-diagnosed multiple myeloma patients at single cell resolution. The overall goal of the research in Tom’s lab is to identify novel therapeutic targets in the bone marrow stromal micro-environment to allow for development of therapies aiming at the tumor as well as the supportive environment in which these tumor cells reside.