Neuroscience
Periphery-brain Interplay and CNS Disease
14-15 November 2023, Leuven, Belgium
Periphery-brain Interplay and CNS Disease
Periphery-brain Interplay and CNS Disease
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Roosmarijn Vandenbroucke
Renzo Mancuso
Kiavash Movahedi
Jeroen Raes
Beth Stevens
Evy Vierstraete
This conference edition will be centered around exploring the pivotal role of the periphery-brain interplay in the context of CNS diseases. Traditionally, CNS diseases were believed to originate primarily within the CNS itself. However, emerging research has brought to light the significant influence of peripheral signals on the development and progression of these disorders. During the conference, we will delve deeper into various mechanisms contributing to the periphery-brain interplay in CNS diseases.
Furthermore, the conference will focus on the intricate interplay between the body and the brain, exploring how the body communicates with the brain through various signaling pathways and the subsequent impact on homeostasis.
The following topics will be discussed:
- The gut-brain axis
- Body-brain signaling and impact on homeostasis
- Adaptive & innate immune system interplay in the diseased brain
- Immune surveillance at the brain borders
Travel grants
We offer 4 travel grants to international PhD students, which will reimburse travel costs up to 400 Euros. The deadline to participate is 25 August 2023. The organizing committee notifies the grant winners.
Poster information
The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation. All accepted poster submissions will have a chance to win the Neuron Poster Prize!
Host City: Leuven
Want to know more about the host city of this conference? Find out where the best restaurants, bars, or last-minute print shops are. Check the city page here.
Satellite event
Prior to the conference, there will be a satellite event on Monday 13 November. Find more info on the satellite event, 2nd Belgian Brain Barriers Symposium, here.
Confirmed speakers
Felipe Almeida de Pinho Ribeiro
Felipe Almeida de Pinho Ribeiro
Washington University School of Medicine, US
Beth Stevens
Beth Stevens
Boston Children's Hospital; Broad Institute; Howard Hughes Medical Institute; Harvard University, US
Program
Day 0 (Satellite event) - Monday, 13 November, 2023
More info on the satellite event can be found here: 2nd Belgian Brain Barriers Symposium
08:30
09:00
Welcome coffee and registration
09:00
09:05
Welcome by Maarten Dewilde
09:05
10:30
Young Investigator Session 1 (selected abstracts)
09:05
09:25
Endothelial Wnt/β-catenin signaling controls brain angiogenesis by remodeling the pial basement membrane
Giel Schevenels
Université libre de Bruxelles, BE
Selected from abstracts
09:25
09:45
Identification of direct connections between the dura and the brain
Leon Smyth
Washington University, US
Selected from abstracts
09:45
10:05
Increasing brain half-life of biologicals
Marie-Lynn Cuypers
KU Leuven, BE
Selected from abstracts
10:05
10:25
Transcranial magnetic stimulation restores glial response and microvasculature integrity in experimental Parkinson’s disease
Maria de Carluccio
Catholic University of the Sacred Heart, IT
Selected from abstracts
10:25
10:30
Florence Vanthillo
Revvity, BE
Sponsored talk
10:30
10:50
Coffee break
10:50
12:35
Young Investigator Session 2 (selected abstracts)
10:50
11:10
Breaking barriers: An organised complex 3D in vitro coculture system including key components of the blood-brain barrier
Adrian Seijas
Maastricht University, NL
Selected from abstracts
11:10
11:30
IL-34 empowers regulatory T cells with novel non-canonical function to safeguard brain barrier integrity
Lien Van Hoecke
VIB Center for Inflammation Research, BE
Selected from abstracts
Janne Verreycken
Hasselt University, BE
Selected from abstracts
11:30
11:50
Study of the impact of neutrophiles on the blood-brain barrier in Epilepsy
Coraly Simoes Da Gama
Sorbonne University, FR
Selected from abstracts
11:50
12:10
Evaluation of the in vitro compatibility of plasma with hiPSC-derived microvascular endothelial cells
Sophie-Charlotte Nelz
University Medical Center Rostock, DE
Selected from abstracts
12:10
12:30
A scalable, nanotechnology enabled in vitro blood brain barrier model
Mar Cóndor
IMEC, BE
Selected from abstracts
12:30
12:35
Alex van der Houven
Genscript, UK
Sponsored talk
12:35
14:00
Lunch and poster session
14:00
14:45
Keynote lecture
Leveraging physiology and engineering for drug delivery to the brain: taking antibodies, enzymes and other proteins to the final frontier
Robert Thorne
Denali Therapeutics, US
Keynote speaker
14:45
15:30
Keynote lecture
Assessment of the extent of drug transport across the barriers of the central and peripheral nervous systems: methodological considerations
Irena Loryan
Uppsala University, SE
Keynote speaker
15:30
15:45
Poster award and closing of the satellite event
15:45
17:00
Networking reception
Meet and greet keynote speakers BBBelgium and selected speakers Periphery-brain Interplay and CNS Disease Conference.
Julie Siegenthaler
University of Colorado, US
Jane Foster
UT Southwestern Medical Center, US
More info on the satellite event can be found here.
Day 1 (Conference) - Tuesday, 14 November, 2023
08:30
09:00
Welcome coffee & Registration
09:00
09:15
Welcome
09:15
12:50
Session 1:The gut-brain axis
09:15
09:45
Pushing the boundaries of central nervous system immunity
Menna R Clatworthy
University of Cambridge, UK
09:45
10:15
Gut Feelings: The Microbiome as a Key Regulator of Brain & Behaviour Across the Lifespan
John Cryan
University College Cork, IE
10:15
10:45
Leveraging the microbiome to understand clinical heterogeneity in depression
Jane Foster
UT Southwestern Medical Center, US
10:45
11:00
Gut Macrophages Modulate Brain Neuropathology in Parkinson’s disease
Sebastiaan De Schepper
UK Dementia Research Institute, University College London, UK
Selected from abstracts
11:00
11:35
Coffee break
11:35
12:05
The gut-microbiota-brain axis: a role for the brain barriers?
Roosmarijn Vandenbroucke
VIB-UGent Center for Inflammation Research, BE
12:05
12:35
Neuro-immune interaction and aberrant pain signalling in the gut
Guy Boeckxstaens
KU Leuven, UZ Leuven, BE
12:35
12:50
The role of LRRK2 in the peripheral immune system and the gut-to-brain axis in Parkinson's disease
Veerle Baekelandt
KU Leuven, BE
Selected from abstracts
12:50
13:50
Lunch
13:50
15:00
Poster session 1
15:00
17:50
Session 2: Adaptive & innate immune system interplay in the diseased brain
15:00
15:30
Regulatory CNS cell-cell interactions in health and disease
Francisco Quintana
Brigham and Women’s Hospital, Harvard Medical School, US
15:30
16:00
Systemic immune response during Parkinson’s disease
Marina Romero-Ramos
Aarhus University, DK
16:00
16:15
Generation of Yolk-sac-like myeloid progenitors models the heterogeneous landscape of human myeloid ontogeny
Anna Martinez Muriana
VIB-KU Leuven Center for Brain & Disease Research, BE; Department of Neurosciences and Leuven Brain Institute, KU Leuven, BE
Selected from abstracts
16:15
16:50
Coffee break
16:50
17:20
A microglia’s fate in Alzheimer’s disease
Michael Heneka
University of Luxembourg, LU
17:20
17:50
Adaptive immunity in neurodegenerative disease
David Gate
Northwestern University, US
17:50
17:55
No-wash immunoassays for all your scientific challenges
Florence Vanthillo
Revvity, BE
Sponsored talk
17:55
19:00
Reception
19:00
Social activity + conference dinner (20h00)
Additional fee
Day 2 (Conference) - Wednesday, 15 November, 2023
08:30
09:00
Welcome coffee & Registration
09:00
12:35
Session 3: Immune surveillance at the brain borders
09:00
09:30
Brain’s periphery at the central stage of brain-immune communication
Jony Kipnis
Washington University School of Medicine in St.Louis, US
09:30
10:00
Life and function of macrophages at the brain border
Melanie Greter
University of Zurich, CH
10:00
10:30
The paradox of IL-12 in Neuroinflammation
Burkhard Becher
University of Zurich, CH
10:30
10:45
Microglia ontogeny and phenotype is influenced by the unique micro-environment of the circumventricular organs
Hannah Van Hove
VUB, BE; Institute of Experimental Immunology, University of Zürich, CH
Selected from abstracts
10:45
11:20
Coffee break
11:20
11:50
Fibroblast-immune cell cross-talk in CNS development and inflammation
Julie Siegenthaler
University of Colorado, US
11:50
12:20
Neuroimmune signalling determining synaptic fate in neurodegenerative diseases
Soyon Hong
UK Dementia Research Institute at University College London, UK
12:20
12:35
IL-34 empowers regulatory T cells with novel non-canonical function to safeguard brain barrier integrity
Lien Van Hoecke
VIB Center for Inflammation Research, BE
Selected from abstracts
12:35
13:30
Lunch
13:30
14:30
Poster session 2
14:30
17:20
Session 4 : Body-brain signaling and impact on homeostasis
14:30
15:00
When brain borders take center stage: role of meningeal macrophages in neuroinflammation and neurodevelopment
Rejane Rua
Centre d’Immunologie de Marseille-Luminy, FR
15:00
15:30
Uncommon Senses: New Mechanisms of Immune Regulation by the Sensory Nervous System
Felipe Almeida de Pinho Ribeiro
Washington University School of Medicine, US
15:30
15:45
A brain-to-skin axis orchestrates dermal macrophages healing properties.
Guillaume Hoeffel
Centre d'Immunologie de Marseille Luminy (CIML), FR
Selected from abstracts
15:45
16:00
An early life fibroblast niche orchestrates hematopoiesis at the brain’s borders
Alec J. Walker
Boston Children's Hospital, US; Harvard Medical School, US; Broad Institute of MIT and Harvard, US
Selected from abstracts
16:00
16:30
Coffee break
16:30
17:00
Acute systemic inflammation causes delirium, new brain injury and accelerated dementia
Colm Cunningham
Trinity College Dublin, IE
17:00
17:30
How Neuro-Immune Signaling Mediates Neuronal Protein Homeostasis in the Aging Brain
Beth Stevens
Boston Children's Hospital; Broad Institute; Howard Hughes Medical Institute; Harvard University, US
17:30
17:40
Closing remarks & Poster prize ceremony
Organizing committee
Roosmarijn Vandenbroucke
VIB-UGent Center for Inflammation Research, BE
Renzo Mancuso
VIB-UAntwerp Center for Molecular Neurology, BE
Kiavash Movahedi
VUB, BE
Jeroen Raes
VIB-KU Leuven Center for Microbiology, BE
Beth Stevens
Boston Children's Hospital; Broad Institute; Howard Hughes Medical Institute; Harvard University, US
Evy Vierstraete
VIB Headquarters, BE
Abstracts
The full list of abstracts will be available on 31-10-2023 until 15-01-2024
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Attendees
The full list of attendees will be available on 31-10-2023 until 15-01-2024
This list will only be available for registered attendees of the event.
This list will only be available for registered attendees of the event.
Sponsors
Silver
Silver
