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Part of the conference series

Type 2 Immunity in Homeostasis and Disease

21-22 February 2019, Bruges, Belgium
Campaign image - Type 2 Immunity in Homeostasis and Disease
Markt - Bruges
Markt - Bruges
Poster session - Bruges
Poster session - Bruges
Old St. John Conference room - Bruges
Old St. John Conference room - Bruges
Drafting course - Bruges
Drafting course - Bruges
City Hall - Bruges
City Hall - Bruges
Markt - Bruges
Markt - Bruges
Dijver river - Bruges
Dijver river - Bruges
Old St. John venue - Bruges
Old St. John venue - Bruges
Type 2 Immunity in Homeostasis and Disease

In cooperation with Cell Press

Type 2 inflammation rich in eosinophils, basophils and mast cells and orchestrated by Th2 lymphocytes has been mainly studied in the context of allergies and immune responses to helminths. Since the discovery of type 2 innate lymphoid cells there has been a strong interest in understanding how type 2 immunity is induced and regulated, for example by barrier epithelial cells.

Given the recent introduction of new biologics that target type 2 cytokines to treat severe allergic disease, we are accumulating a lot of new insights on type 2 immune responses in humans as well.

This meeting will not only focus on new effector and regulatory mechanisms of the type 2 immune response. It will also offer a number of talks taking a broader look on type 2 immunity, dealing with such topics as type 2 immunity in homeostasis, growth and repair, metabolism, neuro-immune interactions and cancer.

Understanding these alternative roles for type 2 immunity will be important to address the benefits and potential pitfalls of long-term inhibition of type 2 immunity by biologicals and could elucidate new therapeutic pathways for very common diseases like asthma, obesity, diabetes and cancer.

Abstracts can be submitted for the following topics:

  • Tissue homeostasis and repair
  • Type 2 Neuro-immune axis
  • Type 2 in allergy, asthma & helminth infection
  • Type 2 Immunity & Cancer

Meet the Editor

We offer all attendees the opportunity to join our ‘Meet the Editor' session with Bruce Koppelman (Senior Scientific Editor Immunity, US). During an informal round table discussion on the 21st of February (15:25 - 15:55), You will have the opportunity to ask Bruce any question about the editorial process. Are you interested in joining the session, then send an e-mail to conferences@vib.be.

Information for poster submissions:

The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation

You can find the poster list here.

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Confirmed speakers

Judi Allen
Allen Judi - profile picture
Judi Allen

Judi Allen

Lydia Becker Institute for Immunology & Inflammation, The University of Manchester, UK
Ariel Munitz
Munitz Ariel - profile page
Ariel Munitz

Ariel Munitz

Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, IL

Program

Day 1 - Thursday, 21 February, 2019

08:30
09:00
Welcome coffee and registration
Opening Keynote
09:00
09:50
Benefit of mast cells and IgE during innate and acquired immune responses to venoms. Is this the "good side" of allergy?
Session 1: Type 2 Neuro - immune axis
09:50
10:25
Neuro-immune interaction in abdominal pain: from bench to bedside

Guy Boeckxstaens

Translational Research Center for GI Disorders (TARGID), UZ Leuven, KU Leuven, BE
10:25
10:55
Coffee break
10:55
11:30
Interleukin-33 promotes microglial-mediated synapse remodeling during brain development and learning
11:30
12:05
Sympathetic neuroimmunity in Obesity

Ana Domingos

Dept. Physiology, Anatomy, Genetics, University of Oxford, UK
12:05
12:05
Sponsored talk: SygRNA® chemically synthesized two-part and single CRISPR guide RNAs for robust genome editing
12:10
13:00
Lunch
13:00
14:00
Poster Session
Session 2: Tissue homeostasis and repair
14:00
14:35
ILC2 in the regulation of adaptive immunity and metabolism
14:35
15:10
Chitinase-like proteins and IL-17A: sculptors of the type 2 immune response

Judi Allen

Lydia Becker Institute for Immunology & Inflammation, The University of Manchester, UK
15:10
15:25
Selected Talk: IgM is required for IL-4 dependent expansion of macrophages in the pleural cavity
15:25
15:55
Coffee break & Meet the Editor session
15:55
16:30
Type 2 immune priming of insulin secretion
16:30
17:05
The Anamnestic response of Pathological Lung Resident Memory Th2 cells responding to allergen
Closing talk
17:05
17:40
ILC2s and dedicated tissue circuits
17:50
18:30
Guided tour to the Bruges City Hall (for dinner participants)
18:30
19:30
Reception at Bruges City Hall (for dinner participants)
20:00
22:30
Conference Dinner @ Halve Maan (Sold Out)

Day 2 - Friday, 22 February, 2019

08:30
09:00
Welcome coffee and registration
Session 3: Type 2 in Allergy, Asthma & helminth infection
09:00
09:35
Interleukin-33 (IL-33): a tissue-derived nuclear cytokine with critical roles in allergic inflammation
09:35
10:10
IL-4 Production of Group 2 Innate Lymphoid Cells

Kazuyo Moro

Laboratory for Innate Immune systems, RIKEN IMS, JP
10:10
10:25
Selected Talk: Allergic immune responses can increase host defense against bacteria
10:25
10:55
Coffee break
10:55
11:30
Antigen-specific T cell population dynamics in response to food allergen immunotherapy
11:30
12:05
Immune Regulation at barrier surfaces
12:05
12:40
Intestinal epithelial tuft cells: sentinels of the gut mucosa
12:40
12:55
Selected Talk: Repertoire and single cell analysis of lymphoid- and nonlymphoid-resident CD4+ T cells in the context anti-helminth immunity
12:55
13:00
Sponsored Talk: VectorBuilder: The future of cloning and virus packaging
13:00
13:50
Lunch
13:50
14:50
Poster Session
Session 4: Type 2 Immunity & Cancer
15:25
15:40
Selected Talk: IL-33 activates anti-tumoral toxicity in eosinophils through stimulation of contact-dependent degranulation
15:40
16:10
Coffee break
16:10
16:45
Emerging roles for eosinophils in the tumor microenvironment

Ariel Munitz

Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, IL
16:45
17:20
maging-based insights into Innate and Adaptive Type 2 Immunity

Ronald N. Germain

National Institute of Allergy and Infectious Diseases, National Institutes of Health, US
Closing Talk
17:20
17:55
Spontaneous protein crystallization as a drugable target in type 2 immunity

Organizing committee

Abstracts

The full list of abstracts will be available on 14-02-2019 until 28-02-2019
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 14-02-2019 until 28-02-2019
This list will only be available for registered attendees of the event.