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Part of the conference series

The Brain Mosaic: cellular heterogeneity in the CNS

22-23 September 2016, Leuven, Belgium
Campaign image - The Brain Mosaic: Cellular heterogeneity in the CNS (2nd edition)
Posters NGAPA17
Posters NGAPA17
M Museum - Leuven
M Museum - Leuven
Poster session - Antwerp
Poster session - Antwerp
Old Market Leuven (copyright Rob Stevens KUL)
Old Market Leuven (copyright Rob Stevens KUL)
Social activities - Leuven
Social activities - Leuven
City Hall Leuven
Networking
Networking
Networking
Networking
The Brain Mosaic: cellular heterogeneity in the CNS

Advances in genomics through to in vivo physiology allow us, for the first time, to explore cellular heterogeneity at multiple experimental levels. Nowhere is this more important than in the Central Nervous System (CNS), where cellular heterogeneity has profound effects on all aspects of normal brain function and behavior, and explains important aspects of disease pathology.

This neuroscience meeting assembles leaders in the field of single cell analysis, together with junior faculty, post-doctoral fellows and graduate students. We will discuss both cutting-edge technological developments in single cell analysis and what they reveal about CNS function and disease.

Meet the Expert session with: ‘Amita Sehgal - University of Pennsylvania, US’

We offer all junior researchers the opportunity to join our ‘Meet the Expert' session with Amita Sehgal. During an informal round table discussion on the 22nd of September (17:00-17:30), PhD students and postdocs will have the exclusive opportunity to ask any question/advise related to their research and careers. If you are interested in joining the session, then send an e-mail to conferences@vib.be. Seating is very limited so make sure to reserve a spot soon.

The conference will be preceded by a training day for graduate students and post-doctoral researchers, which will introduce junior researchers to essential techniques used in the field.

In addition to a great scientific and training program, there will be ample opportunities to network during the breaks, poster sessions, Meet the Expert-session and conference dinner.

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Confirmed speakers

Program

Day 1 - Thursday, 22 September, 2016

09:00
09:25
Registration & coffee
09:30
13:20
Session 1: The CNS one cell at a time: single cell sequencing and cell diversity
09:30
10:30
Molecular anatomy of the brain by large-scale single-cell RNA-seq
11:00
11:30
Coffee Break
11:30
12:00
Dissecting heterogeneity of neuronal injury responses via Single Cell Genomics
12:00
12:30
Div-Seq: Single nucleus RNA-Seq reveals dynamics of rare adult newborn neurons
12:30
13:00
Genome-wide changes in lncRNA, alternative splicing and cortical patterning and shifts in the expression of marker genes, in autism
13:00
13:15
Selected abstract: A molecular taxonomy of the mouse retina using single cell transcriptomics
13:20
15:00
Lunch & Poster session (Odd numbers)
15:00
16:30
Session 2: Mapping diversity in the CNS: spatial transcriptomics
15:00
15:30
Single cell approaches to understanding human neocortical cell types and local circuit connectivity

Ed Lein

Allen Institute for Brain Science, US
15:30
16:00
Positional information of gene expression in the brain cancer and development
16:00
16:30
Spatially resolved gene expression heterogeneity in tissue sections
16:30
17:00
Coffee Break
16:30
17:00
Meet the Expert: Amita Sehgal

Seating for this session is limited, please send an e-mail to conferences@vib.be if you would like to attend.

17:00
18:00
Session 3: New developments in technology and bioinformatics
17:00
17:15
Selected abstract: By any other name: quantifying neuronal subtype identity through functional meta-analysis
Selected from abstracts
17:15
17:30
Selected Abstract: Gene regulatory network inference from single-cell RNA-seq reveals high- resolution cellular states
17:30
18:00
Computational challenges in single-cell RNA-seq
18:00
19:00
Reception
20:00
23:00
Conference Dinner @ Faculty Club

Day 2 - Friday, 23 September, 2016

08:30
09:00
Welcome Coffee
09:00
12:15
Session 4: CNS disease: can we explain it through sequencing?
09:00
10:00
Somatic mutation and genomic diversity in the human cerebral cortex
10:00
10:30
Cellular variation in brain development and disease

Bassem Hassan

ICM Institute, FR & VIB Center for the Biology of Disease, KU Leuven, BE
10:30
11:00
Coffee Break
11:00
11:30
Understanding gene regulation via chromatin structure in developing human brain
12:00
12:15
Selected Abstract: Defining the neurovascular niche through single cell sequencing
12:15
14:00
Lunch & Poster Session (Even numbers)
14:00
17:15
Session 6: CNS functionality: probing activity at the single cell level
14:00
14:30
Genetic Dissection of Neuron and Glia Genesis using Mosaic Analysis with Double Markers (MADM)
14:30
15:00
Neural Circuits for Adaptive Behaviors

Vanessa Ruta

Laboratory of Neurophysiology and Behavior, The Rockefeller University, US
15:00
15:30
Optogenetics: Lighting Up the Brain
15:30
16:00
Coffee Break
16:00
16:30
Circuits underlying rhythmic rest:activity behavior
16:30
16:45
Selected abstract: SIFamide orchestrates multiple peptidergic signals into appetitive and feeding behavior in Drosophila

Thomas Riemensperger

Department of Molecular Neurobiology of Behavior, Georg-August- Universität Göttingen. DE
Selected from abstracts
16:45
17:15
All-optical interrogation of neural circuits
17:15
17:30
Closing Remarks

Organizing committee

Mark Fiers

VIB-KU Leuven Center for Brain & Disease Research, BE

Abstracts

The full list of abstracts will be available on 01-01-1970 until 01-01-1970
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 01-01-1970 until 01-01-1970
This list will only be available for registered attendees of the event.